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Titolo:
THROMBOMODULIN DISTRIBUTION DURING MURINE DEVELOPMENT
Autore:
FORD VA; WILKINSON JE; KENNEL SJ;
Indirizzi:
OAK RIDGE NATL LAB,DIV BIOL OAK RIDGE TN 37830 OAK RIDGE NATL LAB,DIV BIOL OAK RIDGE TN 37830 UNIV TENNESSEE,OAK RIDGE GRAD SCH BIOMED SCI OAK RIDGE TN 37830 UNIV TENNESSEE,SCH VET KNOXVILLE TN 37996
Titolo Testata:
Roux's archives of developmental biology
fascicolo: 6, volume: 202, anno: 1993,
pagine: 364 - 370
SICI:
0930-035X(1993)202:6<364:TDDMD>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROTEIN-C ACTIVATION; NATURAL ANTICOAGULANT; FETAL DEVELOPMENT; FACTOR-V; THROMBIN; LUNG; DOMAIN; IDENTIFICATION; FETOMODULIN; ENDOTHELIUM;
Keywords:
THROMBOMODULIN EXPRESSION; MURINE DEVELOPMENT; ANGIOGENESIS; MONOCLONAL ANTIBODIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
V.A. Ford et al., "THROMBOMODULIN DISTRIBUTION DURING MURINE DEVELOPMENT", Roux's archives of developmental biology, 202(6), 1993, pp. 364-370

Abstract

Thrombomodulin is a transmembrane glycoprotein involved in the regulation of clot formation. Previous work has shown that in the adult mouse, thrombomodulin expression is primarily located on the luminal surface of endothelial cells; whereas during development, thrombomodulin has been localized to the placental parietal endoderm, the neuroepithelium, head mesenchyme, lung bud, and atrium of Day 10.5 post coitum embryos. We examined the expression of thrombomodulin in the adult mouse and throughout murine development from Day 7.5 to Day. 18.5 post coitum. The high expression of thrombomodulin in the lung bud, developing gonads, leptomeninges, and the parietal endoderm in comparison to the expression levels in the adult organs suggest that thrombomodulin may play an important role in development.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 06:24:00