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Titolo:
RAT PROLACTIN-LIKE PROTEIN-A PARTIAL GENE AND PROMOTER STRUCTURE - PROMOTER ACTIVITY IN PLACENTAL AND PITUITARY-CELLS
Autore:
VUILLE JC; CATTINI PA; BOCK ME; VERSTUYF A; SCHROEDTER IC; DUCKWORTH ML; FRIESEN HG;
Indirizzi:
UNIV MANITOBA,FAC MED,DEPT PHYSIOL,770 BANNATYNE AVE WINNIPEG R3E 0W3MANITOBA CANADA UNIV MANITOBA,FAC MED,DEPT PHYSIOL,770 BANNATYNE AVE WINNIPEG R3E 0W3MANITOBA CANADA CATHOLIC UNIV LEUVEN,REGA INST MED RES B-3000 LOUVAIN BELGIUM
Titolo Testata:
Molecular and cellular endocrinology
fascicolo: 1-2, volume: 96, anno: 1993,
pagine: 91 - 98
SICI:
0303-7207(1993)96:1-2<91:RPPPGA>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
GROWTH-HORMONE GENE; COMPLEMENTARY DEOXYRIBONUCLEIC-ACID; TRANSCRIPTION FACTOR; CDNA CLONE; CHORIONIC SOMATOMAMMOTROPIN; MOLECULAR-CLONING; BOVINE PLACENTA; TUMOR-CELLS; LACTOGEN-II; POU-DOMAIN;
Keywords:
PROLACTIN; PLACENTA; GENE; CELL-SPECIFIC REGULATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
44
Recensione:
Indirizzi per estratti:
Citazione:
J.C. Vuille et al., "RAT PROLACTIN-LIKE PROTEIN-A PARTIAL GENE AND PROMOTER STRUCTURE - PROMOTER ACTIVITY IN PLACENTAL AND PITUITARY-CELLS", Molecular and cellular endocrinology, 96(1-2), 1993, pp. 91-98

Abstract

Rat prolactin-like protein A (rPLP-A) is a member of a rapidly expanding family of prolactin-related proteins that are expressed during pregnancy by the rat placenta according to specific developmental patterns. Although the factors involved in the pituitary-specific expression of the prolactin and growth hormone genes themselves have been extensively studied, essentially nothing is known of the factors responsible for the placental expression of these new family members. In this paper we describe the isolation of rPLP-A genomic clones, analyze a portion of the 5' flanking sequence of this gene and use the recently described rat choriocarcinoma cell line, Rcho, in transient transfection studies to show that a 975 base-pair (bp) fragment of 5' flanking sequence is sufficient to specify placental expression of the rPLP-A gene.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/10/20 alle ore 00:37:27