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Titolo:
APPLICATION OF THE RATIO SPECTRA DERIVATIVE SPECTROPHOTOMETRY TO THE ANALYSIS OF CEPHRADINE AND CLAVULANIC ACID IN BINARY-MIXTURES
Autore:
MURILLO JA; LEMUS JM; GARCIA LF;
Indirizzi:
CASTILLA LA MANCHA UNIV,DEPT ANALYT CHEM & FOOD TECHNOL E-13071 CIUDAD REAL SPAIN CASTILLA LA MANCHA UNIV,DEPT ANALYT CHEM & FOOD TECHNOL E-13071 CIUDAD REAL SPAIN
Titolo Testata:
Fresenius' journal of analytical chemistry
fascicolo: 3-4, volume: 347, anno: 1993,
pagine: 114 - 118
SICI:
0937-0633(1993)347:3-4<114:AOTRSD>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPECTROMETRY; RESOLUTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Murillo et al., "APPLICATION OF THE RATIO SPECTRA DERIVATIVE SPECTROPHOTOMETRY TO THE ANALYSIS OF CEPHRADINE AND CLAVULANIC ACID IN BINARY-MIXTURES", Fresenius' journal of analytical chemistry, 347(3-4), 1993, pp. 114-118

Abstract

A new spectrophotometric method has been applied for resolving binarymixtures of cephradine (CED) and clavulanic acid (CA). The method is based on the use of the first derivative of the ratio spectra obtainedby dividing the amplitudes, at appropriate wavelengths, of the absorption spectra of the mixtures by those of a standard solution of clavulanic acid for determining cephradine and a standard solution of cephradine for determining clavulanic acid. Beer's law is obeyed for cephradine concentrations up to 56.0 mg/l and for clavulanic acid concentrations up to 32.0 mg/l. The recovery values of cephradine and clavulanic acid in their 6:1 and 1:4 (m/m) mixtures were satisfactory.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 06:45:24