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Titolo:
GREEN BANANA PROTECTION OF GASTRIC-MUCOSA AGAINST EXPERIMENTALLY-INDUCED INJURIES IN RATS - A MULTICOMPONENT MECHANISM
Autore:
DUNJIC BS; SVENSSON I; AXELSON J; ADLERCREUTZ P; ARRAJAB A; LARSSON K; BENGMARK S;
Indirizzi:
LUND UNIV,DEPT SURG S-22185 LUND SWEDEN LUND UNIV,DEPT SURG S-22185 LUND SWEDEN LUND UNIV,DEPT FOOD TECHNOL S-22185 LUND SWEDEN LUND UNIV,DEPT BIOTECHNOL S-22185 LUND SWEDEN
Titolo Testata:
Scandinavian journal of gastroenterology
fascicolo: 10, volume: 28, anno: 1993,
pagine: 894 - 898
SICI:
0036-5521(1993)28:10<894:GBPOGA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
BARRIER; ACID; CYTOPROTECTION; INDOMETHACIN; SURFACTANT; SUCRALFATE; SECRETION;
Keywords:
BANANA FRUIT; CHRONIC ULCER; ETHANOL; GASTRIC MUCOSA; INDOMETHACIN; MUCOSAL EROSIONS; MUCOSAL PROTECTION; PECTIN; PHOSPHATIDYLCHOLINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
B.S. Dunjic et al., "GREEN BANANA PROTECTION OF GASTRIC-MUCOSA AGAINST EXPERIMENTALLY-INDUCED INJURIES IN RATS - A MULTICOMPONENT MECHANISM", Scandinavian journal of gastroenterology, 28(10), 1993, pp. 894-898

Abstract

The protective capacities of fresh green (unripe) sweet bananas and of phosphatidylcholine and pectin (banana ingredients) against acute (ethanol- or indomethacin-induced) and chronic (indomethacin-induced) gastric mucosal lesions were evaluated in rats. Banana pulp was mixed with saline and given by gavage, as a pretreatment in a single dose. Theidentical protocol was used for pectin and phosphatidylcholine solution, and the dosages were adjusted to equal the amount of ingredients in the banana mixture, but higher concentrations were also given. The banana suspension reduced acute lesions, as did pectin and phosphatidylcholine in higher concentrations, but in concentrations as in fresh fruit no protective effects were observed except by pectin against indomethacin injury. In the model of chronic ulcers the banana suspension provided an incomplete and temporary protective effect. We conclude that the protective capacity of fresh green sweet bananas cannot be confined to only one active component. Pectin and phosphatidylcholine may protect gastric mucosa by strengthening the mucous-phospholipid layer, but the mechanism of protection afforded by bananas has to be further elucidated.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 06:52:58