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Titolo:
IMMUNOELECTROPHORETIC DIFFERENTIATION OF ALPHA-FETOPROTEIN IN DISORDERS WITH ELEVATED SERUM ALPHA-FETOPROTEIN LEVELS OR DURING PREGNANCY
Autore:
CHEN RJ; CHEN CK; CHANG DY; CHOW SN; HUANG SC; HSIEH CY; LIN MC; HSU HC;
Indirizzi:
NATL TAIWAN UNIV HOSP,DEPT OBSTET & GYNECOL,7 CHUNG SHAN S RD TAIPEI TAIWAN NATL TAIWAN UNIV HOSP,DEPT OBSTET & GYNECOL TAIPEI TAIWAN NATL TAIWAN UNIV HOSP,DEPT PATHOL TAIPEI 100 TAIWAN NATL TAIWAN UNIV HOSP,LASER MED RES CTR TAIPEI 100 TAIWAN
Titolo Testata:
Acta oncologica
fascicolo: 7, volume: 34, anno: 1995,
pagine: 931 - 935
SICI:
0284-186X(1995)34:7<931:IDOAID>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
LECTIN-AFFINITY ELECTROPHORESIS; GERM-CELL TUMORS; HUMAN YOLK-SAC; HEPATOCELLULAR-CARCINOMA; EARLY DIAGNOSIS; CONCANAVALIN-A; SUGAR CHAINS; SUBFRACTIONS; MICROHETEROGENEITY; SPECIFICITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
R.J. Chen et al., "IMMUNOELECTROPHORETIC DIFFERENTIATION OF ALPHA-FETOPROTEIN IN DISORDERS WITH ELEVATED SERUM ALPHA-FETOPROTEIN LEVELS OR DURING PREGNANCY", Acta oncologica, 34(7), 1995, pp. 931-935

Abstract

Our study aims to make differential diagnosis by immunoelectrophoresis for some common conditions ,vith elevated levels of serum alpha-fetoprotein (AFP), One hundred and nine cases with elevated AFP levels were included in this study: yolk sac tumor (n = 8), hepatocellular carcinoma (n = 26), gastric cancer (n = 12), chronic hepatitis (n = 27) andnormal pregnancy (n = 36), Lectin agarose gel electrophoresis, antibody-affinity blotting, and immunoreaction were used to identify the specific patterns of AFP in the respective conditions. The results showedthat there were three possible bands: L1, L2 and L3. Yolk sac tumor produced a prominent L2 band and a light L3 band, Hepatocellular carcinoma produced a prominent L1 band and a light L3 band, Gastric cancer produced only an LI band, Chronic hepatitis had a light L1 band and a pronounced L3 band. In pregnancy, the AFP pattern is similar to that ofhepatocellular carcinoma, Immunoelectrophoresis is a useful method facilitating the differentiation of AFP origins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 13:20:40