Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
TONIC TRANSMITTER RELEASE IN A GRADED POTENTIAL SYNAPSE
Autore:
UUSITALO RO; JUUSOLA M; KOUVALAINEN E; WECKSTROM M;
Indirizzi:
UNIV OULU,DEPT PHYSIOL OULU FINLAND
Titolo Testata:
Journal of neurophysiology
fascicolo: 1, volume: 74, anno: 1995,
pagine: 470 - 473
SICI:
0022-3077(1995)74:1<470:TTRIAG>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOWFLY PHOTORECEPTORS; POTASSIUM CHANNELS; LIGHT ADAPTATION; SODIUM-PUMP; CALLIPHORA; HISTAMINE; RETINA; CELL; FLY;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
R.O. Uusitalo et al., "TONIC TRANSMITTER RELEASE IN A GRADED POTENTIAL SYNAPSE", Journal of neurophysiology, 74(1), 1995, pp. 470-473

Abstract

1. We studied graded synaptic transmission in the fly photoreceptor-interneuron synapse by using intracellular in situ recordings from pre-and postsynaptic cells. 2. A large presynaptic hyperpolarization after Light adaptation, caused by the activation of the electrogenic Na+/K pump, drastically reduced the conspicuous postsynaptic dark noise. At the same time, the postsynaptic neurons depolarized, with an increase of input resistance of 5-10 M Omega. 3. The spectral characteristicsof the postsynaptic membrane noise in dark and during noise reduction, together with the other results, suggested that the transmitter release decreased dramatically similar to 12 mV below the resting potential of the presynaptic photoreceptors. 4. During the postsynaptic noise reduction, the saturated and subsaturated first-order visual interneuron responses were increased up to 9 mV with a time constant of recovery of similar to 10 s. This increase was shown to be caused by the negative shift of the reversal potential of the transmitter-gated (mainly Cl-) conductance, caused apparently by the reduced transmitter input. 5. The results strongly suggest that the photoreceptor transmitter release in fly is tonic, even in dark, and further support the modulationof the synaptic voltage transfer by postsynaptic Cl-extrusion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 10:27:33