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Titolo:
EFFECT OF ETHANOL-CONSUMPTION ON ADULT-RAT LIVER MITOCHONDRIAL POPULATIONS ANALYZED BY FLOW-CYTOMETRY
Autore:
MATEOS A; ORFAO A; ALMEIDA A; MARTIN MI; LOPEZMEDIAVILLA C; MEDINA JM; FERMOSO J;
Indirizzi:
HOSP UNIV SALAMANCA,HEMATOL LAB,SERV GEN CITOMETRIA E-37007 SALAMANCASPAIN UNIV SALAMANCA,DEPT MED,CYTOMETRY UNIT E-37008 SALAMANCA SPAIN UNIV SALAMANCA,DEPT BIOCHEM & MOLEC BIOL E-37008 SALAMANCA SPAIN
Titolo Testata:
Alcoholism, clinical and experimental research
fascicolo: 5, volume: 19, anno: 1995,
pagine: 1327 - 1330
SICI:
0145-6008(1995)19:5<1327:EOEOAL>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENERGY-METABOLISM; LIVING CELLS; MEMBRANE; RHODAMINE-123; ALCOHOL; MEGAMITOCHONDRIA; IDENTIFICATION; FLUORESCENCE; DISEASE; BRAIN;
Keywords:
ALCOHOL; RAT LIVER; MITOCHONDRIA; FLOW CYTOMETRY; RHODAMINE-123;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
38
Recensione:
Indirizzi per estratti:
Citazione:
A. Mateos et al., "EFFECT OF ETHANOL-CONSUMPTION ON ADULT-RAT LIVER MITOCHONDRIAL POPULATIONS ANALYZED BY FLOW-CYTOMETRY", Alcoholism, clinical and experimental research, 19(5), 1995, pp. 1327-1330

Abstract

In the present study, the effects of administering ethanol to adult male rats on the distribution of the low fluorescence population (LFP) and high fluorescence population (HFP), and the rhodamine-123 fluorescence intensity of these groups of mitochondria are analyzed by flow cytometry, Our results show that ethanol administration to adult male rats induces a redistribution of the HFP and LFP mitochondrial populations leading to an increase of the less functional HFP mitochondria, In addition, ethanol induced an increase in the mean intensity of green fluorescence of the HFP that is probably related to an increased numberof rhodamine-123 binding sites per mitochondria resulting from mitochondria enlargement.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:21:15