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Titolo:
MITE ALLERGEN (DER-P-1) CONCENTRATION IN HOUSES AND ITS RELATION TO THE PRESENCE AND SEVERITY OF ASTHMA IN A POPULATION OF SYDNEY SCHOOLCHILDREN
Autore:
MARKS GB; TOVEY ER; TOELLE BG; WACHINGER S; PEAT JK; WOOLCOCK AJ;
Indirizzi:
UNIV SYDNEY,DEPT MED SYDNEY NSW 2006 AUSTRALIA
Titolo Testata:
Journal of allergy and clinical immunology
fascicolo: 4, volume: 96, anno: 1995,
pagine: 441 - 448
SICI:
0091-6749(1995)96:4<441:MA(CIH>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
DUST MITES; AUSTRALIAN SCHOOLCHILDREN; BRONCHIAL HYPERRESPONSIVENESS; RESPIRATORY SYMPTOMS; SEASONAL-VARIATION; EXPOSURE; CHILDREN; DERMATOPHAGOIDES; PREVALENCE; ANTIGEN;
Keywords:
ASTHMA; ALLERGENS; HOUSE DUST MITE; RISK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
G.B. Marks et al., "MITE ALLERGEN (DER-P-1) CONCENTRATION IN HOUSES AND ITS RELATION TO THE PRESENCE AND SEVERITY OF ASTHMA IN A POPULATION OF SYDNEY SCHOOLCHILDREN", Journal of allergy and clinical immunology, 96(4), 1995, pp. 441-448

Abstract

House dust mite (HDM) allergen exposure and its relation to HDM allergy and asthma was assessed BE a case-control study conducted over three seasons in 74 Sydney schoolchildren, 33 of whom were allergic to HDMand 12 of whom had current asthma. In each season, histamine inhalation tests and skin prick tests were performed, symptom questionnaires were administered, and dust samples were collected. The mean concentrations of HDM allergen (in micrograms of Der p I PEI. gram of fine dust)were: bed, 38.9 (95% confidence interval [CI] 31.8 to 47.5); bedroom floor; 22.4 (95% CI, 18.3 to 27.5); nod lounge room floor; 13.7 (95% CI, 10.7 to 17.6). The mean of the highest allergen concentration in each house was 51.0 (95% CI, 43.2 to 60.1). All brit two subjects had atleast one site in all seasons within HDM allergen concentration greater than 10 mu g/gm, the proposed threshold for asthma symptoms. Subjects with allergy to HDM, symptoms of asthma, or airway hyperresponsiveness did not have higher HDM allergen concentrations in their houses. In this study we were unable to test hypotheses concerning proposed thresholds for risk of sensitization and for risk of asthma symptoms because virtually all subjects were exposed to HDM allergen levels above the proposed thresholds.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 13:57:56