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Titolo:
HEMOPHILIC ARTHROPATHY OF THE KNEE-JOINT - STATIC AND DYNAMIC GD-DTPA- ENHANCED MRI
Autore:
NAGELE M; BRUNING R; KUNZE V; EICKHOFF H; KOCH W; REISER M;
Indirizzi:
TURMSTR 21 D-77933 LAHR GERMANY UNIV BONN,DEPT RADIOL W-5300 BONN GERMANY UNIV MUNICH,DEPT RADIOL MUNICH GERMANY DEPT ORTHOPED SURG TROISDORF GERMANY
Titolo Testata:
European radiology
fascicolo: 5, volume: 5, anno: 1995,
pagine: 547 - 552
SICI:
0938-7994(1995)5:5<547:HAOTK->2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
RHEUMATOID-ARTHRITIS;
Keywords:
HEMOPHILIA; KNEE JOINT; SYNOVIAL PROLIFERATION; MR STUDIES; GADOLINIUM; CONTRAST ENHANCEMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
M. Nagele et al., "HEMOPHILIC ARTHROPATHY OF THE KNEE-JOINT - STATIC AND DYNAMIC GD-DTPA- ENHANCED MRI", European radiology, 5(5), 1995, pp. 547-552

Abstract

A total of 17 patients with hemophilic arthropathy of the knee joint were studied with static and dynamic MRI before and after an IV bolus injection of Gadolinium-DTPA (Gd-DTPA; 0.1 mmol/kg body weight). The T1-weighted spin-echo (SE) and gradient-echo (fast-field echo [FFE] sequences were applied. The FFE sequences of eight consecutive scans carried out over a time interval of 160 s were used in order to determine the time to signal intensity (SI) curves of the synovial proliferations surrounding soft tissue, bone marrow, and joint effusion. After the administration of a contrast agent, synovial proliferations exhibited an increase on FFE and SE images of 47.7% (SD +/- 14.3%) and 37.4% (SD+/- 11.2%), respectively, whereas muscle and fatty tissue, tendons, bone marrow, and joint effusion revealed only a minor increase in SI. The gradient of SI (ratio SI/time) of pannus was 39.6%/min (SD +/- 7.7%/min) and differed significantly (P<0.001) from that of bone marrow, fatty tissue, muscle tissue, tendons, and joint effusion (P<0.05). In contrast to synovial proliferations in rheumatoid arthritis, no differentiation between various pannus vascularities based on the degree of enhancement was possible. The Gd-DTPA-enhanced MRI studies delineate and quantify the synovial proliferations in hemophilic arthropathy. Dynamic studies in hemophilic arthropathy do not provide qualitative assessment of the inflammatory process.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 07:17:47