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Titolo:
BARTONELLA (ROCHALIMAEA) ANTIBODIES, DEMENTIA, AND CAT OWNERSHIP AMONG MEN INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS
Autore:
SCHWARTZMAN WA; PATNAIK M; ANGULO FJ; VISSCHER BR; MILLER EN; PETER JB;
Indirizzi:
VET AFFAIRS MED CTR,DEPT MED,INFECT DIS SECT,16111 PLUMMER ST SEPULVEDA CA 91343 UNIV CALIF LOS ANGELES,SCH PUBL HLTH,DEPT MED LOS ANGELES CA 90024 UNIV CALIF LOS ANGELES,INST NEUROPSYCHIAT LOS ANGELES CA 90024 LOS ANGELES CTR MULTICTR AIDS COHORT STUDY LOS ANGELES CA 00000 VET AFFAIRS MED CTR,DEPT MED,INFECT DIS SECT SEPULVEDA CA 00000 SPECIALTY LABS SANTA MONICA CA 00000
Titolo Testata:
Clinical infectious diseases
fascicolo: 4, volume: 21, anno: 1995,
pagine: 954 - 959
SICI:
1058-4838(1995)21:4<954:B(ADAC>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
HENSELAE SP-NOV; SCRATCH DISEASE; BACILLARY ANGIOMATOSIS; PELIOSIS HEPATIS; HOMOSEXUAL MEN; NEURORETINITIS; AIDS; ENCEPHALOPATHY; PATIENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
W.A. Schwartzman et al., "BARTONELLA (ROCHALIMAEA) ANTIBODIES, DEMENTIA, AND CAT OWNERSHIP AMONG MEN INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS", Clinical infectious diseases, 21(4), 1995, pp. 954-959

Abstract

To determine the association between recent human immunodeficiency virus (HIV)-associated dementia and serum antibodies to Bartonella (Rochalimaea) henselae, we performed a nested case control study within theMulticenter AIDS Cohort Study in Los Angeles. We measured serum IgG and IgM antibodies to B. henselae with use of enzyme immunoassay in 369HIV-seropositive and HIV-seronegative participants with and without recent neuropsychological deterioration. Data on pet ownership were also collected. IgM antibodies to B. henselae were strongly associated with neuropsychological decline or dementia (OR = 6.6; 95% CI = 1.4-31.9; P = .02), Those participants with IgM antibodies to B. henselae were1.7 times more likely to develop HIV-associated dementia (HAD) or neuropsychological decline over the next 5 years. At least 4% of the new cases of HAD and neuropsychological decline were due to bartonella infection, Cat ownership was associated with the presence of IgM antibodies to B. henselae (OR = 6.4; 95% CI = 1.3-30.8; P = .02) and with neuropsychological decline and dementia (OR = 2.4; 95% CI = 1.2-5.1; P = .02), This finding suggests that some cases of HAD and neuropsychological decline are associated with potentially treatable B. henselae infections.

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Documento generato il 30/11/20 alle ore 03:18:41