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Titolo:
VASOPRESSIN AND THE ENDOCRINE RESPONSE TO STRESS
Autore:
ANTONI FA;
Indirizzi:
UNIV EDINBURGH,DEPT PHARMACOL,MRC,BRAIN METAB UNIT EDINBURGH EH8 9JZ MIDLOTHIAN SCOTLAND
Titolo Testata:
Netherlands journal of zoology
fascicolo: 1-2, volume: 45, anno: 1995,
pagine: 98 - 102
SICI:
0028-2960(1995)45:1-2<98:VATERT>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
PITUITARY; BINDING; RAT; RECEPTORS; SECRETION;
Keywords:
CORTICOTROPIN-RELEASING FACTOR; INTRACELLULAR FREE CALCIUM; CAMP; PITUITARY GLAND; HYPOTHALAMIC-PITUITARY-ADRENOCORTICAL AXIS; CORTICOSTEROID FEEDBACK;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
F.A. Antoni, "VASOPRESSIN AND THE ENDOCRINE RESPONSE TO STRESS", Netherlands journal of zoology, 45(1-2), 1995, pp. 98-102

Abstract

This paper highlights the role of vasopressin in the endocrine response to stress at various levels of regulation in the hypothalamic-pituitary-adrenocortical system. Novel data are presented regarding the interaction of vasopressin and corticotropin-releasing factor (CRF) in rat anterior pituitary cells. In this system CRF-induced cyclic AMP synthesis is under feedback inhibition by intracellular free calcium. Vasopressin enhances the cyclic AMP response to CRF apparently by reducingthe efficiency of calcium inhibition. As corticosteroid mediated inhibition of ACTH release is also mediated by a calcium-dependent process, these findings show a mechanism whereby vasopressin may change the set-point of glucocorticoid negative feedback at the pituitary level.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:47:51