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Titolo:
HEPATIC LYMPH-NODES AS A FOLLOW-UP FACTOR IN PRIMARY BILIARY-CIRRHOSIS - AN ULTRASOUND STUDY
Autore:
LYTTKENS K; PRYTZ H; FORSBERG L; HAGERSTRAND I;
Indirizzi:
UNIV LUND HOSP,DEPT DIAGNOST RADIOL S-22185 LUND SWEDEN UNIV LUND HOSP,DEPT INTERNAL MED S-22185 LUND SWEDEN UNIV LUND HOSP,DEPT PATHOL S-22185 LUND SWEDEN
Titolo Testata:
Scandinavian journal of gastroenterology
fascicolo: 10, volume: 30, anno: 1995,
pagine: 1036 - 1040
SICI:
0036-5521(1995)30:10<1036:HLAAFF>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIAL;
Keywords:
CHOLESTASIS; HEPATOCELLULAR DAMAGE; HUMORAL IMMUNOREACTIVITY; INTRALOBULAR INFLAMMATION; URSODEOXYCHOLIC ACID;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
K. Lyttkens et al., "HEPATIC LYMPH-NODES AS A FOLLOW-UP FACTOR IN PRIMARY BILIARY-CIRRHOSIS - AN ULTRASOUND STUDY", Scandinavian journal of gastroenterology, 30(10), 1995, pp. 1036-1040

Abstract

Background: The aim of this study was to investigate whether changes in lymph node size in the hepatoduodenal ligament reflect changes in biochemical and histologic markers of cholestasis, hepatocellular damage, and humoral immunoreactivity in patients with primary biliary cirrhosis (PBC). Methods: Twenty-three consecutive patients were examined with repeated liver biopsies, laboratory tests, and ultrasonographic examinations of the hepatoduodenal ligament. The effect of treatment with ursodeoxycholic acid (UDCA) on these factors was also studied. Results: A correlation was found between changes in lymph node size and changes in markers of hepatocellular damage, cholestasis, and humoral immunoreactivity and also with intralobular inflammation. In the UDCA-treated patients the node size decreased slightly during 2 years of treatment, whereas it was unchanged in the control group (p = 0.0528). Conclusions: Changes in the size of the lymph nodes in the hepatoduodenal ligament may reflect inflammation and cholestasis in PBC and thus be avaluable indicator in the followup of patients with this disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:55:48