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Titolo:
MEASUREMENT OF SERUM TROPONIN-T, CREATINE-KINASE MB ISOENZYME, AND TOTAL CREATINE-KINASE FOLLOWING ARDUOUS PHYSICAL-TRAINING
Autore:
COLLINSON PO; CHANDLER HA; STUBBS PJ; MOSELEY DS; LEWIS D; SIMMONS MD;
Indirizzi:
MAYDAY UNIV HOSP,DEPT CHEM PATHOL,MAYDAY HOSP CROYDON CR7 7YE SURREY ENGLAND INST NAVAL MED ALVERSTOKE HANTS ENGLAND CHARING CROSS & WESTMINSTER MED SCH,DEPT ACAD CARDIOL LONDON ENGLAND UNIV HOSP ISLEWORTH ISLEWORTH MIDDX ENGLAND
Titolo Testata:
Annals of clinical biochemistry
, volume: 32, anno: 1995,
parte:, 5
pagine: 450 - 453
SICI:
0004-5632(1995)32:<450:MOSTCM>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; UNSTABLE ANGINA; DIAGNOSIS; RISK; EXERCISE; MASS;
Keywords:
CK-MB MASS; MYOCARDIAL INFARCTION; CARDIAC ENZYMES; RELATIVE INDEX; SKELETAL MUSCLE TRAUMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
P.O. Collinson et al., "MEASUREMENT OF SERUM TROPONIN-T, CREATINE-KINASE MB ISOENZYME, AND TOTAL CREATINE-KINASE FOLLOWING ARDUOUS PHYSICAL-TRAINING", Annals of clinical biochemistry, 32, 1995, pp. 450-453

Abstract

We have compared measurement of cardiac troponin T by enzyme linked immunosorbent assay with creatine kinase MB isoenzyme (CK-MB) concentration measurement in 219 Royal Marine commandos with no evidence of cardiovascular disease who have elevated creatine kinase (CK) produced byarduous physical training. CK was elevated up to 22.6 times and CK-MBmass up to 6.6 times the upper reference limit. Only two commandos had detectable cardiac troponin T, with neither exceeding the upper reference limit of 0.2 mu g/L. At decision thresholds optimized for diagnosis of acute myocardial infarction in previous published work, 58.3% of the total CK activity, 13.8% of the CK-MB concentration/CK activity ratio and 1.6% of CK-MB concentration measurements showed elevated values but no elevations in cardiac troponin T occurred. Cardiac troponinT is currently the investigation of choice for the differential diagnosis of patients with an elevated CK due to skeletal muscle trauma to exclude myocardial damage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 07:46:10