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Titolo:
BLOOD OXYGENATION DEPENDENCE OF T-1 AND T-2 IN THE ISOLATED, PERFUSEDRABBIT HEART AT 4.7T
Autore:
ATALAY MK; REEDER SB; ZERHOUNI EA; FORDER JR;
Indirizzi:
JOHNS HOPKINS UNIV,SCH MED,DEPT RADIOL & RADIOL SCI,NMR,DIV RES,217 TRAYLOR BLDG,720 RUTLAND AVE BALTIMORE MD 21205 JOHNS HOPKINS UNIV,SCH MED,DEPT RADIOL & RADIOL SCI,NMR,DIV RES BALTIMORE MD 21205 JOHNS HOPKINS UNIV,SCH MED,DEPT BIOMED ENGN BALTIMORE MD 21205
Titolo Testata:
Magnetic resonance in medicine
fascicolo: 4, volume: 34, anno: 1995,
pagine: 623 - 627
SICI:
0740-3194(1995)34:4<623:BODOTA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
SENSORY STIMULATION; BRAIN; CONTRAST; MYOCARDIUM; RELAXATION; TIME;
Keywords:
FUNCTIONAL MRI; MYOCARDIAL OXYGEN CONTENT; MYOCARDIAL IMAGING;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
M.K. Atalay et al., "BLOOD OXYGENATION DEPENDENCE OF T-1 AND T-2 IN THE ISOLATED, PERFUSEDRABBIT HEART AT 4.7T", Magnetic resonance in medicine, 34(4), 1995, pp. 623-627

Abstract

An MR line scan protocol has been used to measure relaxation parameters (T-1 and T-2) in isolated, blood perfused rabbit hearts at various blood oxygenations, Hearts were retrogradely perfused at 37 degrees C with a cardioplegic solution (modified St, Thomas' solution) containing sheep red blood cells and adenosine (1 mM) to maximally vasodilate the coronary vascular bed, Arresting the hearts eliminated motion complications and minimized arteriovenous oxygenation differences, The authors have found that under conditions of stable flow, there is a strongcorrelation between T-2 in myocardial septa and hemoglobin (Hb) saturation, while tissue T-1 is virtually independent of blood oxygenation. These effects are believed to be due to the paramagnetic agent deoxyhemoglobin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 16:26:33