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Titolo:
INFLUENCE OF DRYING CONDITIONS ON RESIDUAL SOLVENT CONTENTS IN CRYSTALS .1. STUDY ON MONOCRYSTALLINE PARTICLES
Autore:
BARTHELEMY C; DIMARTINO P; GUYOTHERMANN AM;
Indirizzi:
UNIV LILLE 2,FAC SCI PHARMACEUT & BIOL,PHARM GALEN & BIOPHARM LAB,3 RUE PROF LAGUESSE,BP 83 F-59006 LILLE FRANCE UNIV LILLE 2,FAC SCI PHARMACEUT & BIOL,PHARM GALEN & BIOPHARM LAB F-59006 LILLE FRANCE
Titolo Testata:
Die Pharmazie
fascicolo: 9, volume: 50, anno: 1995,
pagine: 607 - 609
SICI:
0031-7144(1995)50:9<607:IODCOR>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
4
Recensione:
Indirizzi per estratti:
Citazione:
C. Barthelemy et al., "INFLUENCE OF DRYING CONDITIONS ON RESIDUAL SOLVENT CONTENTS IN CRYSTALS .1. STUDY ON MONOCRYSTALLINE PARTICLES", Die Pharmazie, 50(9), 1995, pp. 607-609

Abstract

Nowadays the research of residual solvents present in a pharmaceutical substance is highly recommended by the authorities. The objective was to evaluate the influence of drying conditions on the content of volatile impurities. Several drying processes were carried out on paracetamol recrystallized in three different solvents. The determination of the residual solvent concentration has shown important variations according to the drying processes. The technological properties of the different crystals obtained were also investigated. Compression behaviourdoes not seem to be influenced by the residual solvent content.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 20:26:32