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Titolo:
STUDIES ON THE TYROSINE-BASED POLYPHOSPHA TE ANTITUMOR DRUGS
Autore:
FAN CL; HU B; ZHUO RX; DU Y;
Indirizzi:
WUHAN UNIV,DEPT CHEM WUHAN 430072 PEOPLES R CHINA WUHAN UNIV,DEPT CHEM WUHAN 430072 PEOPLES R CHINA
Titolo Testata:
Gaodeng xuexiao huaxue xuebao
fascicolo: 1, volume: 18, anno: 1997,
pagine: 149 - 153
SICI:
0251-0790(1997)18:1<149:SOTTPT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
CHI
Keywords:
POLYPHOSPHATE; TYROSINE; AMPHIPHILICITY; 5-FLUOROURACIL; METHOTREXATE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
C.L. Fan et al., "STUDIES ON THE TYROSINE-BASED POLYPHOSPHA TE ANTITUMOR DRUGS", Gaodeng xuexiao huaxue xuebao, 18(1), 1997, pp. 149-153

Abstract

New polyphosphate antitumor durgs containing 5-Fu or MTX were synthesized by macromolecular reaction of polyphosphates with the corresponding drug molecules. All these polyphosphates obtained are amphiphilic, some of them have micelle-forming properties. The hydrolysis and in vitro drug release properties of these polyphosphates were studied. The in vitro antitumor activity data showed that some of these polyphosphates exhibit good antitumor activity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 00:52:39