Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A KERATAN SULFATE PROTEOGLYCAN MARKS THE BOUNDARIES IN THE CORTICAL BARREL FIELDS OF THE ADULT-RAT
Autore:
SEO HY; GEISERT EE;
Indirizzi:
UNIV TENNESSEE,CTR HLTH SCI,DEPT ANAT & NEUROBIOL MEMPHIS TN 38163 UNIV TENNESSEE,CTR HLTH SCI,DEPT ANAT & NEUROBIOL MEMPHIS TN 38163
Titolo Testata:
Neuroscience letters
fascicolo: 1, volume: 197, anno: 1995,
pagine: 13 - 16
SICI:
0304-3940(1995)197:1<13:AKSPMT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; CORTEX; ASTROCYTES; MOUSE;
Keywords:
CNS KERATAN SULFATE PROTEOGLYCAN; BARREL; BOUNDARY; ADULT RAT; SYNAPTIC STABILIZATION; NEURONAL REGENERATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
H.Y. Seo e E.E. Geisert, "A KERATAN SULFATE PROTEOGLYCAN MARKS THE BOUNDARIES IN THE CORTICAL BARREL FIELDS OF THE ADULT-RAT", Neuroscience letters, 197(1), 1995, pp. 13-16

Abstract

The present study uses the monoclonal antibody TED 15 to examine the distribution of a keratan sulfate proteoglycan, ABAKAN, in the barrel field of the rat somatosensory cortex. At birth there is very little ABAKAN present in the somatosensory cortex. The levels of this proteoglycan increase during development until the highest levels are reached in the adult rat. Immunohistochemistry reveals that the TED 15 immunoreaction product marks the boundaries between cortical barrels. At postnatal day 7 (P7) the proteoglycan is localized specifically to the boundary regions. As the brain matures, the levels of ABAKAN increase in the barrel hollows and in the surrounding cortex; however the boundaryregions maintain a higher level of expression even in the adult animal. The high levels of ABAKAN observed in the adult barrel fields indicate that unlike other boundary molecules this proteoglycan may be involved in maintaining the structure of the adult somatosensory cortex.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 08:42:02