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Titolo:
SHORT-TERM POSTISCHEMIC HYPOPERFUSION IMPROVES RECOVERY OF PROTEIN-SYNTHESIS IN THE RAT-BRAIN CORTEX
Autore:
BURDA J; GOTTLIEB M; VANICKY I; CHABKO M; MARSALA J;
Indirizzi:
SLOVAK ACAD SCI,INST NEUROBIOL,SOLTESOVEJ 6 KOSICE 04001 SLOVAKIA
Titolo Testata:
Molecular and chemical neuropathology
fascicolo: 2-3, volume: 25, anno: 1995,
pagine: 189 - 198
SICI:
1044-7393(1995)25:2-3<189:SPHIRO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; CEREBRAL BLOOD-FLOW; SPINAL-CORD; PROLONGED ISCHEMIA; CAT BRAIN; OXYGEN; REPERFUSION; DAMAGE; INJURY; POLYRIBOSOMES;
Keywords:
CEREBRAL ISCHEMIA; PROTEIN SYNTHESIS; REPERFUSION INJURY; HYPOPERFUSION; GRADED REOXYGENATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
43
Recensione:
Indirizzi per estratti:
Citazione:
J. Burda et al., "SHORT-TERM POSTISCHEMIC HYPOPERFUSION IMPROVES RECOVERY OF PROTEIN-SYNTHESIS IN THE RAT-BRAIN CORTEX", Molecular and chemical neuropathology, 25(2-3), 1995, pp. 189-198

Abstract

A cell-free system from rat brain cortex was used to follow changes in protein synthesis after ischemia and reperfusion (four-vessel occlusion). The experiment was focused to prevent a violent burst of free oxygen radicals creation during the first period of postischemic reperfusion by short-Germ hypoperfusion. After 30 min of ischemia, the authors applied hypoperfusion produced by releasing one (right) carotid for the first 5 min of reperfusion lasting from 30 min to 3 d. Results obtained by this procedure show that the activity of protein synthesis machinery from hypoperfused brains is higher than normovolemic ones; theleft hemisphere, which is contralateral to direct blood flow during hypoperfusion, shows better results than the right hemisphere.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:27:04