Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CEREBRAL BLOOD-FLOW AND METABOLISM IN HYPERTENSIVE PATIENTS WITH CEREBRAL INFARCTION
Autore:
NAKANE H; IBAYASHI S; FUJII K; IRIE K; SADOSHIMA S; FUJISHIMA M;
Indirizzi:
KYUSHU UNIV,FAC MED,DEPT INTERNAL MED 2,HIGASHI KU,MAIDASHI 3-1-1 FUKUOKA 812 JAPAN
Titolo Testata:
Angiology
fascicolo: 9, volume: 46, anno: 1995,
pagine: 801 - 810
SICI:
0003-3197(1995)46:9<801:CBAMIH>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
TERM ANTIHYPERTENSIVE TREATMENT; CEREBROVASCULAR-DISEASE; RATS; PRESSURE; THERAPY; BRAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
H. Nakane et al., "CEREBRAL BLOOD-FLOW AND METABOLISM IN HYPERTENSIVE PATIENTS WITH CEREBRAL INFARCTION", Angiology, 46(9), 1995, pp. 801-810

Abstract

The authors investigated, by positron emission tomography, the effectof long-standing hypertension on cerebral blood flow (CBF) and oxygenmetabolism in patients with chronic atherothrombotic brain infarction. In the nonbrain infarct (non-BI) group (n=13, mean age: sixty-two years), the regional CBF (rCBF) was decreased significantly with a rise in the mean arterial blood pressure (MABP) in the cerebral cortexes (r=-0.575) and the deep gray matter (r=-0.451), whereas the regional cerebral metabolic rate for oxygen (rCMRO2) remained unchanged. In the brain infarct (BI) group (n=22, mean age: fifty-eight years), however, the rCBF as well as the rCMRO2 were reduced even in the normotensive patients and thus did not correlate with the MABP. These results suggestthat long-standing hypertension per se causes a reduction in the rCBFbut not in the oxygen metabolism with a compensatory increase in the oxygen extraction fraction. On the other hand, patients with brain infarction, even normotensives, show a diffuse decrease in cerebral circulation and metabolism, which is probably due to the more severe sclerotic changes that take place in the cerebral vessels.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 08:49:58