Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
PROSPECTIVE RANDOMIZED COMPARATIVE-STUDY OF PULSE-SPRAY AND CONVENTIONAL LOCAL THROMBOLYSIS
Autore:
YUSUF SW; WHITAKER SC; GREGSON RHS; WENHAM PW; HOPKINSON BR; MAKIN GS;
Indirizzi:
UNIV NOTTINGHAM HOSP,DEPT VASC SURG NOTTINGHAM NG7 2UH ENGLAND
Titolo Testata:
European journal of vascular and endovascular surgery
fascicolo: 2, volume: 10, anno: 1995,
pagine: 136 - 141
SICI:
1078-5884(1995)10:2<136:PRCOPA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
S.W. Yusuf et al., "PROSPECTIVE RANDOMIZED COMPARATIVE-STUDY OF PULSE-SPRAY AND CONVENTIONAL LOCAL THROMBOLYSIS", European journal of vascular and endovascular surgery, 10(2), 1995, pp. 136-141

Abstract

Objectives: To compare the rime required to achieve lysis with the pulse spray technique and the conventional slow continuous infusion technique. Design: Prospective randomised open Study. Methods: Eighteen patients suitable for intra-arterial thrombolytic therapy with conventional and pulse spray technique were randomised 1:1 to receive either pulse spray thrombolysis with 0.33 mg/ml rt-PA injected as a bolus of 0.2 ml or conventional thrombolysis with 0.05 mg/ml rt-PA infused at a rate of 10 ml/h. Results: The age, duration of symptoms, length of occlusion and prethrombolysis ankle brachial pressure index were comparable in the two groups. The median duration of thrombolytic therapy in the pulse spray group was 195 min (range 90-1260) compared to 1390 min (range 300 - 2400) in the Conventional group. The difference between the two groups was significant, p<0.002 (Mann-Whitney test). Conclusions: Significantly shorter lime is required to achieve local thrombolysiswith pulse spray compared to the conventional infusion method.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 09:00:11