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Titolo:
MITOCHONDRIAL ATP SYNTHASE ALPHA-SUBUNIT GENE AMPLIFIED IN A RETINOBLASTOMA CELL-LINE MAPS TO CHROMOSOME-18
Autore:
BIE WJ; SQUIRE JA; FRASER M; PATERSON MC; GODBOUT R;
Indirizzi:
CROSS CANC INST,MOLEC ONCOL PROGRAM,11560 UNIV AVE EDMONTON AB T6G 1Z2 CANADA CROSS CANC INST,MOLEC ONCOL PROGRAM EDMONTON AB T6G 1Z2 CANADA UNIV ALBERTA,DEPT ONCOL EDMONTON AB CANADA UNIV TORONTO,HOSP SICK CHILDREN,DEPT PATHOL TORONTO ON M5G 1X8 CANADA
Titolo Testata:
Genes, chromosomes & cancer
fascicolo: 1, volume: 14, anno: 1995,
pagine: 63 - 67
SICI:
1045-2257(1995)14:1<63:MASAGA>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
N-MYC; INSITU HYBRIDIZATION; HUMAN NEUROBLASTOMAS; DNA-SEQUENCES; C-MYC; AMPLIFICATION; EXPRESSION; AMPLICONS; PRECURSOR; MUTATION;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
W.J. Bie et al., "MITOCHONDRIAL ATP SYNTHASE ALPHA-SUBUNIT GENE AMPLIFIED IN A RETINOBLASTOMA CELL-LINE MAPS TO CHROMOSOME-18", Genes, chromosomes & cancer, 14(1), 1995, pp. 63-67

Abstract

The human retinoblastoma cell line Y79 has multiple copies of the MYCN gene and the DEAD box gene DDXI. Both genes have been mapped to chromosome band 2p24. A third gene, encoding the alpha-subunit of mitochondrial ATP synthase (ATPSA), is also amplified in Y79. Here we report that there are at least four human mitochondrial ATPSA-related genes located on four different chromosomes. The ATPSA gene that is amplified in Y79 originates from chromosome 18. In Y79, the amplified copies of both the ATPSA and the MYCN genes are located on a homogeneously staining region (HSR) at chromosome band 1p34. (C) 1995 Witey-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 08:11:50