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Titolo:
GIANT-CELL TUMOR OF THE PANCREAS ARISING IN THE OVARIAN-LIKE STROMA OF A MUCINOUS CYSTADENOCARCINOMA
Autore:
BERGMAN S; MEDEIROS LJ; RADR T; MANGHAM DC; LEWANDROWSKI KB;
Indirizzi:
MASSACHUSETTS GEN HOSP,DEPT PATHOL,GRAY 5 BOSTON MA 02114 MASSACHUSETTS GEN HOSP,DEPT PATHOL BOSTON MA 02114 HARVARD UNIV,SCH MED BOSTON MA 00000 RHODE ISL HOSP,DEPT PATHOL PROVIDENCE RI 02902 BROWN UNIV,SCH MED PROVIDENCE RI 02912
Titolo Testata:
International journal of pancreatology
fascicolo: 1, volume: 18, anno: 1995,
pagine: 71 - 75
SICI:
0169-4197(1995)18:1<71:GTOTPA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Keywords:
GIANT CELL TUMOR; PANCREAS; MUCINOUS CYSTIC NEOPLASM; CYSTIC TUMOR; MUCINOUS CYSTADENOCARCINOMA;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
S. Bergman et al., "GIANT-CELL TUMOR OF THE PANCREAS ARISING IN THE OVARIAN-LIKE STROMA OF A MUCINOUS CYSTADENOCARCINOMA", International journal of pancreatology, 18(1), 1995, pp. 71-75

Abstract

We describe a malignant mucinous cystic neoplasm of the pancreas withovarian-like stroma within which an osteoclast-like giant cell rich tumor arose. This rare tumor had a unique immunohistochemical profile with the giant cells staining for vimentin, leukocyte common antigen, and the monocyte/macrophage marker CD68, whereas the mucinous epithelium stained for epithelial membrane antigen and cytokeratin. The immunohistochemical findings are consistent with two lines of differentiation, one epithelial and the other suggesting mesenchymal differentiation of the giant cell tumor with an immunophenotype similar to giant cell tumor of bone. The coexistence of these two rare tumors suggests that they are histogenetically related. The finding of a giant cell tumor arising in the ovarian stroma indicates that the stroma of mucinous tumors is not always an innocuous component of the tumor.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:33:18