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Titolo:
CARDIOVASCULAR-RESPONSE TO MENTAL STRESS IN OFFSPRING OF HYPERTENSIVEPARENTS - THE DUTCH HYPERTENSION AND OFFSPRING STUDY
Autore:
DEVISSER DC; VANHOOFT IMS; VANDOORNEN LJP; HOFMAN A; ORLEBEKE JF; GROBBEE DE;
Indirizzi:
ERASMUS UNIV ROTTERDAM,SCH MED,DEPT EPIDEMIOL & BIOSTAT,POB 1738 3000DR ROTTERDAM NETHERLANDS ERASMUS UNIV ROTTERDAM,SCH MED,DEPT EPIDEMIOL & BIOSTAT 3000 DR ROTTERDAM NETHERLANDS FREE UNIV AMSTERDAM,DEPT PHYSIOL PSYCHOL AMSTERDAM NETHERLANDS
Titolo Testata:
Journal of hypertension
fascicolo: 8, volume: 13, anno: 1995,
pagine: 901 - 908
SICI:
0263-6352(1995)13:8<901:CTMSIO>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
NORMOTENSIVE SUBJECTS; CARDIAC-OUTPUT; BLOOD-FLOW; PRESSURE; IMPEDANCE; ADOLESCENTS; CHILDREN; SYSTEM; HEMODYNAMICS; PARAMETERS;
Keywords:
PARENTAL HISTORY OF HYPERTENSION; CARDIOVASCULAR REACTIVITY; MENTAL STRESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
49
Recensione:
Indirizzi per estratti:
Citazione:
D.C. Devisser et al., "CARDIOVASCULAR-RESPONSE TO MENTAL STRESS IN OFFSPRING OF HYPERTENSIVEPARENTS - THE DUTCH HYPERTENSION AND OFFSPRING STUDY", Journal of hypertension, 13(8), 1995, pp. 901-908

Abstract

Objective: To compare blood pressure-regulating mechanisms during mental stress in two groups of offspring with contrasting risk for hypertension. Design: Cardiovascular reactivity to two different types of mental stressors was studied in adolescents and young adults with two hypertensive or two normotensive parents. The two tasks used were intended to evoke either a predominantly adrenergic cardiac response (a memory search task) or a predominantly vascular response (a reaction-time task with visual search and tone avoidance) Methods: Blood pressure and heart rate were recorded at rest and during stress. To study adaptations of the cardiovascular system to mental stress, cardiac output, total peripheral resistance and indices of vagal and sympathetic influences on the heart were measured. Results: The reactivity of systolic blood pressure (SEP) to the memory search task was significantly higher in offspring of hypertensive parents, which resulted in a longer recovery after the task. In contrast, during the reaction-time task, offspring of hypertensive parents had a significantly enhanced reactivity ofperipheral resistance, but no differences in heart rate or blood pressure response were observed. No differences between the two groups were found in sympathetic or vagal activity during either task measured by the ratio of pre-ejection time and left ventricular ejection time, and respiratory sinus arrhythmia, respectively. Conclusion: Apart from a higher reactivity of SEP during the memory search task, no other indications supporting the presence of hyperadrenergic activation of the heart in early primary hypertension were found. On the contrary, the results of the present study support the hypothesis that blood pressureresponses in prehypertensive subjects are characterized by enhanced vasoconstriction rather than by increased cardiac output.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:25:56