Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
INFLUENCE OF SODIUM-NITROPRUSSIDE NO-DONOR ON PSYCHOTROPIC ACTIVITY OF ANGIOTENSIN-II
Autore:
WISNIEWSKI K; HOLY Z;
Indirizzi:
POLISH SCH MED,DEPT PHARMACOL,2C MICKIEWICZ STR PL-15222 BIALYSTOK POLAND
Titolo Testata:
Journal of Physiology and Pharmacology
fascicolo: 2, volume: 46, anno: 1995,
pagine: 141 - 150
SICI:
0867-5910(1995)46:2<141:IOSNOP>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
NITRIC-OXIDE SYNTHASE; ANTINOCICEPTIVE ACTIVITY; NEURONAL MESSENGER; BLOOD-PRESSURE; RELEASE; RATS; VASOPRESSIN; INHIBITION; AVOIDANCE; SLICES;
Keywords:
SODIUM NITROPRUSSIDE; NITRIC OXIDE; ANGIOTENSIN II; PSYCHOMOTOR ACTIVITY; CONDITIONED AVOIDANCE RESPONSE; PASSIVE AVOIDANCE; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
K. Wisniewski e Z. Holy, "INFLUENCE OF SODIUM-NITROPRUSSIDE NO-DONOR ON PSYCHOTROPIC ACTIVITY OF ANGIOTENSIN-II", Journal of Physiology and Pharmacology, 46(2), 1995, pp. 141-150

Abstract

In this work we compared the influence of sodium nitroprusside [SNP] (a NO donor) on behavioural effects of angiotensin II [AII] in rats. The motility, stereotypy, learning of conditioned avoidance responses and recall of passive avoidance behaviour allowing to avoid aversive stimulation were estimated. The intracerebroventricularly injection - 15min before the experiment - of AII, SNP and AII combined with SNP didnot produce changes in psychomotor activity in open field, not significantly accelerated acquisition of conditioned avoidance responses andsignificantly improved recall of the passive avoidance. AII, SNP and AII with SNP applied immediately before the experiment intensified stereotypy evoked by apomorphine in the dose of 1 mg/kg and amphetamine in the dose of 7.5 mg/kg given intraperitoneally. These results show that; 1) sodium nitroprusside as a donor NO participates in memory and learning processess, 2) overproduction of NO did not change behaviouraleffects of AII in these experiments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 15:07:41