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Titolo:
DIFFERENTIAL MELANIN-CONCENTRATING HORMONE GENE-EXPRESSION IN 2 HYPOTHALAMIC NUCLEI OF THE TELEOST TILAPIA IN RESPONSE TO ENVIRONMENTAL-CHANGES
Autore:
GRONEVELD D; BALM PHM; MARTENS GJM; BONGA SEW;
Indirizzi:
CATHOLIC UNIV NIJMEGEN,FAC SCI,DEPT ANIM PHYSIOL,TOERNOOIVELD 6525 EDNIJMEGEN NETHERLANDS
Titolo Testata:
Journal of neuroendocrinology
fascicolo: 7, volume: 7, anno: 1995,
pagine: 527 - 533
SICI:
0953-8194(1995)7:7<527:DMHGI2>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
MESSENGER-RIBONUCLEIC-ACID; OREOCHROMIS-MOSSAMBICUS; RAT-BRAIN; RELEASE; TROUT; STRESS; RNA; CORTICOTROPIN; NEUROPEPTIDE; SYSTEM;
Keywords:
MELANIN-CONCENTRATING HORMONE MESSENGER RNA; COLOR CHANGE; STRESS; OSMOREGULATION; CORTISOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
D. Groneveld et al., "DIFFERENTIAL MELANIN-CONCENTRATING HORMONE GENE-EXPRESSION IN 2 HYPOTHALAMIC NUCLEI OF THE TELEOST TILAPIA IN RESPONSE TO ENVIRONMENTAL-CHANGES", Journal of neuroendocrinology, 7(7), 1995, pp. 527-533

Abstract

For some teleosts, a role has been established for melanin-concentrating hormone (MCH) background adaptation and stress response. in teleost fishes, prepro-MCH (ppMCH) mRNA is expressed in the hypothalamus, predominantly in neurons of the nucleus lateralis tuberis (NLT) and in scattered cells of the nucleus recessus lateralis (NRL). The response of mature tilapia to different environmental challenges was studied by assessing ppMCH mRNA levels in these two hypothalamic nuclei by quantitative dot blot analysis. Changes in background colour induced pronounced differences in ppMCH mRNA expression in the NLT, but not in the NRL. The NLT of tilapia adapted to a white background contained 2.5 to 3times more ppMCH mRNA than the NLT of black-adapted fish. The NLT of fish kept on neutral background contained intermediate levels of ppMCHmRNA, which were significantly lower than the levels in white-adaptedfish. Oral administration of dexamethasone lowered plasma cortisol concentrations, but had no effect on ppMCH mRNA levels in white- and black-adapted fish. In tilapia exposed to strongly acidified water (pH 3.5), plasma cortisol and ACTH concentrations were highly elevated, and plasma chloride concentrations considerably lower than in controls. These fish responded with a 70% rise in ppMCH mRNA levels in the NLT, which is most probably associated with a stress response evoked by inadequate osmoregulation. After exposure to a milder acidification (pH 4.0) or to seawater no significant changes in ppMCH mRNA levels occurred in either the NLT or the NRL, nor in plasma chloride, cortisol and ACTH levels. A specific increase of ppMCH mRNA levels in the NRL was observed in repeatedly disturbed tilapia. We conclude that MCH neurons in the NLT and NRL of this teleost differentially respond to background colour, acidification and disturbance stress, and that this response isnot strictly associated with changes in plasma ions and activity of the pituitary-interrenal axis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/11/20 alle ore 21:46:07