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Titolo:
LEIOMYOSARCOMA BONE METASTASIS - A CASE-R EPORT
Autore:
MARICONDA M; TACCHETTI C; MISITI CM; LOTTI G; AMMENDOLIA A; MILLO R; MILANO C;
Indirizzi:
POLICLIN MATERDOMINI,ORTHOPED CLIN,VIA T CAMPANELLA I-88100 CATANZAROITALY UNIV REGGIO CALABRIA,FAC MED,ORTHOPED CLIN REGGIO CALABRIA ITALY
Titolo Testata:
Revue de chirurgie orthopedique et reparatrice de l'appareil moteur
fascicolo: 4, volume: 81, anno: 1995,
pagine: 338 - 343
SICI:
0035-1040(1995)81:4<338:LBM-AC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
FRE
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
M. Mariconda et al., "LEIOMYOSARCOMA BONE METASTASIS - A CASE-R EPORT", Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 81(4), 1995, pp. 338-343

Abstract

Introduction Bone leiomyosarcoma is a rare tumor, whether it may be primary or secondary. The authors report on the case of a woman, aged 67, admitted in January 1992 complaining of pain in the left hip and the upper end of the femur. Case report In 1985 the patient underwent surgical excision of a soft tissue tumor in the right thigh, histologically diagnosed as a benign-fibrous tumor. This lesion recurred locally four times and repeated excisions were performed throughout the years,always with a histological diagnosis of a benign lesion. On admissionto hospital, the physical examination as well as laboratory data and plain roentgenograms were unremarkable. Both tomography and MRI showeda lesion in the upper end of the left femur. An isotopic bone scan showed marked increased uptake in the left hip extending to the femoral diaphysis. An open biopsy was performed for histology, immunohistochemistry and electron microscopy. A diagnosis of metastatic leiomyosarcoma was made. The retrospective histological examination of specimens ofthe soft tissue tumor excised in 1985 showed the same immunohistochemical features of the contralateral leiomyosarcoma. On this basis, one stage resection of the left hip and the upper end of the femur was performed and a Kotz modular prosthesis was inserted. Postoperative healing was achieved without any complications and the function of the operated limb was satisfactory. Three months after the operation pulmonarylesions were noted on chest radiographs and CT scan. The patient diedtwo years after the first admission for widespread metastasis. Discussion In the reported case, the bony metastasis appeared to be the presenting finding of the soft tissue tumor of the controlateral thigh. This presentation is rare in previously published series. The misdiagnosis of the primary tumor had caused focal recurrences, and an increasedmalignity occurred. According to the literature, a soft tissue leiomyosarcoma can be easily confused with other spindle cell lesions. Therefore an accurate histological and ultrastructural diagnosis is necessary for adequate surgical treatment.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 11:12:52