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Titolo:
OSTEOPOROSIS - CLINICAL-ASSESSMENT WITH QUANTITATIVE MR-IMAGING IN DIAGNOSIS
Autore:
WEHRLI FW; FORD JC; HADDAD JG;
Indirizzi:
UNIV PENN,MED CTR,DEPT RADIOL,3400 SPRUCE ST PHILADELPHIA PA 19104 UNIV PENN,MED CTR,DEPT MED PHILADELPHIA PA 19104
Titolo Testata:
Radiology
fascicolo: 3, volume: 196, anno: 1995,
pagine: 631 - 641
SICI:
0033-8419(1995)196:3<631:O-CWQM>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
VERTEBRAL TRABECULAR BONE; COMPUTED-TOMOGRAPHY; MINERAL DENSITY; COMPRESSIVE STRENGTH; REMODELING PROCESS; PROXIMAL FEMUR; FRACTURE RISK; ASH DENSITY; AGE; CONSEQUENCES;
Keywords:
BONES, MR; OSTEOPOROSIS; SPINE, DISEASES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
58
Recensione:
Indirizzi per estratti:
Citazione:
F.W. Wehrli et al., "OSTEOPOROSIS - CLINICAL-ASSESSMENT WITH QUANTITATIVE MR-IMAGING IN DIAGNOSIS", Radiology, 196(3), 1995, pp. 631-641

Abstract

PURPOSE: To determine if the magnetic resonance (MR) imaging effective transverse relaxation rate (R2) of trabecular bone marrow is lowered in osteoporosis. MATERIALS AND METHODS: R2 was measured in 146 women. Control subjects (n = 77; mean age, 46.6 years) had high mean spinal bone mineral densities (BMDs) and no vertebral deformities. Patientswith spinal osteoporosis (n = 59; mean age, 59.7 years) had at least one thoracic vertebral deformity and/or low BMDs. RESULTS: R2 was lower in patients for L-2 through L-5 (P < .001). Average R2 of L-3 through L-5 (R2(av)) was the best discriminator (64.79 sec(-1) +/- 1.18 [standard error] for control subjects vs 53.39 sec(-1) a 1.24 for patients; P < .0001). R2(av) decreased with age in control subjects. The difference in R2(av) in a subset of 38 age-matched pairs of patients and control subjects was 8.25 sec(-1) (P < .0001). Subjects with deformities had lower 52(av) than did control subjects (52.3 sec(-1) +/- 1.6 vs 62.5 sec(-1) +/- 1.1, P < .0001). R2(av) was correlated with mean BMD (r = .54, P < .0001). CONCLUSION: Patients with osteoporosis have lower R2s in vertebral marrow.

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Documento generato il 02/12/20 alle ore 15:12:44