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Titolo:
SARCOLEMMAL CHLORIDE AND POTASSIUM CHANNELS FROM NORMAL AND MYOTONIC MOUSE MUSCLE STUDIED IN LIPID SUPPLEMENTED VESICLES
Autore:
WISCHMEYER E; WEBERSCHURHOLZ S; JOCKUSCH H;
Indirizzi:
UNIV BIELEFELD,DEV BIOL UNIT,W-7 D-33501 BIELEFELD GERMANY UNIV BIELEFELD,DEV BIOL UNIT D-33501 BIELEFELD GERMANY
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 2, volume: 213, anno: 1995,
pagine: 513 - 518
SICI:
0006-291X(1995)213:2<513:SCAPCF>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
SKELETAL-MUSCLE; CONDUCTANCE; MEMBRANES; EXPRESSION; SURFACE; ADR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
E. Wischmeyer et al., "SARCOLEMMAL CHLORIDE AND POTASSIUM CHANNELS FROM NORMAL AND MYOTONIC MOUSE MUSCLE STUDIED IN LIPID SUPPLEMENTED VESICLES", Biochemical and biophysical research communications, 213(2), 1995, pp. 513-518

Abstract

By patch-clamp analysis of lipid supplemented vesicles prepared from the sarcolemma of mouse wildtype skeletal muscle, we could identify two known types of potassium channels, the inward rectifier and Ca2+ activated BK channels, and five types of chloride channels designated GIG-a, CIC-b, CIC-c, CIC-d, and CIC-e. CIC-b corresponds to a known chloride channel, whereas CICa, -c, -d and -e have not been described previously. The diversity may be due to a heterooligomeric composition of different subunits. None of these chloride channels nor the potassium channels were found in the sarcoplasmic reticulum fraction. In vesiclesfrom myotonic mice, Clc-d and -e were not found. (C) 1995 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/10/20 alle ore 01:34:48