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Titolo:
HIGH EARLY PEAK CREATINE-KINASE AFTER THROMBOLYSIS IN PATIENTS WITH ACUTE ANTERIOR INFARCTION PREDICTS POOR LEFT-VENTRICULAR FUNCTION
Autore:
FREIMARK D; MATETZKY S; HOD H; CHOURAGUI P; KAPLINSKY E; RABINOWITZ B;
Indirizzi:
CHAIM SHEBA MED CTR,INST HEART IL-52621 TEL HASHOMER ISRAEL TEL AVIV UNIV,SACKLER SCH MED IL-69978 TEL AVIV ISRAEL
Titolo Testata:
Cardiology
fascicolo: 5, volume: 86, anno: 1995,
pagine: 411 - 416
SICI:
0008-6312(1995)86:5<411:HEPCAT>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYOCARDIAL-INFARCTION; CORONARY-ARTERY REPERFUSION; ENZYMATIC ESTIMATION; MB RELEASE; SHORT-TERM; SIZE; THERAPY; EXTENT; PHOSPHOKINASE; STREPTOKINASE;
Keywords:
CREATINE KINASE, EARLY PEAK; CREATINE KINASE, ABRUPT WASHOUT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
D. Freimark et al., "HIGH EARLY PEAK CREATINE-KINASE AFTER THROMBOLYSIS IN PATIENTS WITH ACUTE ANTERIOR INFARCTION PREDICTS POOR LEFT-VENTRICULAR FUNCTION", Cardiology, 86(5), 1995, pp. 411-416

Abstract

Successful thrombolysis alters the pattern of creatine kinase (CK) release to the plasma after acute myocardial infarction (AMI). Among theimportant differences there are the early peak of the CK activity curve and the higher peak value for a given infarct size. To determine whether the magnitude of peak CK following thrombolysis still reflects the extent of myocardial damage, we correlated the peak CK value with left ventricular ejection fraction (LVEF) in 114 patients with first anterior AMI who had early peak CK(less than or equal to 12 h) after thrombolysis. There was a significant (p < 0.001) linear relation betweenthe peak CK value and LVEF both at admission and 2 months later. High(greater than or equal to 1,500 IU/l) as compared with low early peakCK was associated with significantly lower LVEF (p < 0.001) and a higher incidence of poor LVEF (p < 0.05).

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Documento generato il 22/10/20 alle ore 02:10:40