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Titolo:
NORMAL CONCENTRATIONS OF SERUM INSULIN-LIKE GROWTH-FACTOR-I IN LATE POLIO
Autore:
SUNNERHAGEN KS; BENGTSSON BA; LUNDBERG PA; LANDIN K; LINDSTEDT G; GRIMBY G;
Indirizzi:
GOTHENBURG UNIV,SAHLGRENSKA HOSP,DEPT REHABIL MED,GULDHEDSGATAN 19 S-41345 GOTHENBURG SWEDEN GOTHENBURG UNIV,SAHLGRENSKA HOSP,DEPT INTERNAL MED,DIV ENDOCRINOL S-41345 GOTHENBURG SWEDEN GOTHENBURG UNIV,SAHLGRENSKA HOSP,DEPT CLIN CHEM S-41345 GOTHENBURG SWEDEN
Titolo Testata:
Archives of physical medicine and rehabilitation
fascicolo: 8, volume: 76, anno: 1995,
pagine: 732 - 735
SICI:
0003-9993(1995)76:8<732:NCOSIG>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
POLIOMYELITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
K.S. Sunnerhagen et al., "NORMAL CONCENTRATIONS OF SERUM INSULIN-LIKE GROWTH-FACTOR-I IN LATE POLIO", Archives of physical medicine and rehabilitation, 76(8), 1995, pp. 732-735

Abstract

A recent study of 10 men with postpolio syndrome indicated a low secretion of growth hormone (GH) as reflected by serum insulin-like growthfactor-I (IGF-1). Therefore, 87 patients were studied, 17 to 71 yearsafter acute poliomyelitis, of whom 65% reported the occurrence of newor increased weakness (ie, during the last 2 years) in muscles previously affected by polio. Serum IGF-1 concentrations in the patients were compared with those found in a reference population comprising 392 randomly selected individuals. No differences from the reference population values were observed. No correlation was found between IGF-1 concentrations and the severity of the original polio affliction, the recovery status, the need for ambulation aids, or the presence of new symptoms. The results do not indicate a need for GH substitution treatmentof patients with postpolio syndrome. (C) 1995 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 20:39:48