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Titolo:
INTERNAL CALVARIAL BONE DISTRACTION IN RABBITS WITH EXPERIMENTAL CORONAL SUTURE IMMOBILIZATION - EFFECTS OF OVERDISTRACTION
Autore:
LALIKOS JF; TSCHAKALOFF A; MOONEY MP; LOSKEN HW; SIEGEL MI; LOSKEN A; REITZ P; WRIGHT M;
Indirizzi:
UNIV PITTSBURGH,DEPT ANAT & HISTOL,631 SALK HALL PITTSBURGH PA 15261 UNIV PITTSBURGH,DEPT ANAT & HISTOL PITTSBURGH PA 15261
Titolo Testata:
Plastic and reconstructive surgery
fascicolo: 3, volume: 96, anno: 1995,
pagine: 689 - 698
SICI:
0032-1052(1995)96:3<689:ICBDIR>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL CRANIOSYNOSTOSIS; GROWTH; EXPANSION; SKULL; SYNOSTOSIS; MODELS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Lalikos et al., "INTERNAL CALVARIAL BONE DISTRACTION IN RABBITS WITH EXPERIMENTAL CORONAL SUTURE IMMOBILIZATION - EFFECTS OF OVERDISTRACTION", Plastic and reconstructive surgery, 96(3), 1995, pp. 689-698

Abstract

This study was designed to assess the effects of over-distraction of an experimentally immobilized coronal suture using an internal appliance on craniofacial growth in rabbits. Fifty-three, 1.5-week-old rabbits were used. Markers were placed on either side of the calvarial sutures. Thirty-nine rabbits had bilateral coronal suture immobilization using methyl methacrylate; 14 rabbits served as normal controls. At 6 weeks of age, the 39 immobilized rabbits were randomly assigned to four groups: (1) immobilized controls (n = 14); (2) suturectomy (n = 6); (3) suturectomy with distraction (n = 9);and (4) suturectomy with overdistraction (n = 10). Lateral head radiographs were taken at 1.5, 6, 12,and 18 weeks of age. Results revealed that, by 18 weeks of age, rabbits with overdistraction exhibited significant compensatory growth abnormalities in the cranial vault, midface, and anterior cranial base compared with the other groups. Results indicate that overdistraction maycontribute to craniofacial anomalies through altered growth vectors and compressive tension-stress forces at adjacent sutures and suggest that it may be important to keep ''pace'' with the growing coronal suture and neurocapsular matrix during distraction to reestablish normal craniofacial morphology.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:38:22