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Titolo:
COMPARISON OF SINGLE-TRACER (TECHNETIUM-99M-SESTAMIBI) AND DUAL-TRACER (TL-201 CHLORIDE AND TECHNETIUM-99M-SESTAMIBI) PROTOCOLS FOR IDENTIFICATION OF MYOCARDIAL-ISCHEMIA
Autore:
LOUTFI I; SINGH A;
Indirizzi:
M202,1 HOSP DR COLUMBIA MO 65212 UNIV MISSOURI,HOSP & CLIN,DEPT RADIOL,DIV NUCL MED COLUMBIA MO 00000
Titolo Testata:
Investigative radiology
fascicolo: 6, volume: 30, anno: 1995,
pagine: 367 - 371
SICI:
0020-9996(1995)30:6<367:COS(AD>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; METHOXY ISOBUTYL ISONITRILE; VIABLE MYOCARDIUM; TL-201 SCINTIGRAPHY; REINJECTION; PERFUSION; SPECT; REDISTRIBUTION; EXERCISE;
Keywords:
MYOCARDIAL PERFUSION; RADIOTRACERS; CORONARY ARTERY DISEASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
I. Loutfi e A. Singh, "COMPARISON OF SINGLE-TRACER (TECHNETIUM-99M-SESTAMIBI) AND DUAL-TRACER (TL-201 CHLORIDE AND TECHNETIUM-99M-SESTAMIBI) PROTOCOLS FOR IDENTIFICATION OF MYOCARDIAL-ISCHEMIA", Investigative radiology, 30(6), 1995, pp. 367-371

Abstract

BACKGROUND. The objective of this study was to determine if dual-tracer protocol using thallium-201 ((TI)-T-201) chloride for rest and technetium-99m (Tc-99m)-sestamibi for stress images (TI-MIBI) detects ischemia better than single-tracer protocol using Tc-99m-sestamibi for both rest and stress (MIBI) myocardial perfusion images. METHODS AND RESULTS. A total of 460 patients with suspected or known coronary artery disease (CAD) were included in the study, with 230 (50%) undergoing single-tracer MIBI protocol and 230 (50%) undergoing dual-tracer TI-MIBI protocol, Patient demographics were matched, and the proportion of patients having treadmill stress or dipyridamole stress was similar between the two groups, Stress and rest single photon emission computed tomographic images were recorded in all patients and dual-tracer (TI)-T-201 and Tc-99m-sestamibi (TI-MIBI) perfusion images were acquired separately, The scintigraphic images were analyzed visually, and a semiquantitative method of scoring reversible ischemia was used, Patients' reversibility scores in each group were compiled (ischemia index) and compared to determine the relative ability of each protocol in identifying ischemia. CONCLUSION. The frequency of ischemia and ischemia index was found to be significantly (P < 0.05) higher in the TI-MIBI group compared with the MIBI group, For detecting myocardial ischemia or viability, the dual-tracer TI-MIBI acquisition technique appears superior to the single-tracer MIBI protocol.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 21:50:21