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Titolo:
INTRAVENOUS SEDATION IN PEDIATRIC UPPER GASTROINTESTINAL ENDOSCOPY
Autore:
CHUANG E; WENNER WJ; PICCOLI DA; ALTSCHULER SM; LIACOURAS CA;
Indirizzi:
UNIV PENN,CHILDRENS HOSP PHILADELPHIA,SCH MED,DIV GASTROENTEROL & NUTR,34TH & CIV CTR BLVD PHILADELPHIA PA 19104 UNIV PENN,CHILDRENS HOSP PHILADELPHIA,SCH MED,DIV GASTROENTEROL & NUTR PHILADELPHIA PA 19104
Titolo Testata:
Gastrointestinal endoscopy
fascicolo: 2, volume: 42, anno: 1995,
pagine: 156 - 160
SICI:
0016-5107(1995)42:2<156:ISIPUG>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOUBLE-BLIND TRIAL; CHILDREN; MIDAZOLAM; DIAZEPAM; MEPERIDINE; EFFICACY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
E. Chuang et al., "INTRAVENOUS SEDATION IN PEDIATRIC UPPER GASTROINTESTINAL ENDOSCOPY", Gastrointestinal endoscopy, 42(2), 1995, pp. 156-160

Abstract

To assess the safety and efficacy of intravenous sedation in pediatric upper endoscopy, all elective outpatient procedures performed duringa 2-year period (January 1, 1991 through December 31, 1992) were retrospectively reviewed. Of 614 children, 553 received intravenous meperidine and midazolam; 61 received fentanyl and midazolam. The mean dose of meperidine was 1.5 +/- 0.7 mg/kg and of fentanyl 0.0031 +/- 0.0014 mg/kg. Less midazolam was needed for children receiving fentanyl than for those receiving meperidine (0.05 +/- 0.03 mg/kg versus 0.08 +/- 0.05 mg/kg, p < 002). Recovery time (minutes) was shorter for those receiving fentanyl (74.7 +/- 22.8 versus 95.1 +/- 23.0, p < .003). Side effects occurred in 117 patients (19.1%), of which the majority were mild (83%); all were transient with no residual sequelae. Inability to complete the procedure occurred in fewer than 1%. We conclude that both combinations of medication are safe and effective for children of all ages. The use of fentanyl/midazolam results in a shorter recovery timeand a lower dose of midazolam.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/07/20 alle ore 22:14:50