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Titolo:
RADIOGRAPHIC ABNORMALITIES IN TUBERCULOSIS AND RISK OF COEXISTING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION
Autore:
MLIKACABANNE N; BRAUNER M; KAMANFU G; GRENIER P; NIKOYAGIZE E; AUBRY P; LAROUZE B; MURRAY JF;
Indirizzi:
68 BLVD ST MICHEL F-75006 PARIS FRANCE HOP CLAUDE BERNARD,INSERM,U13 PARIS FRANCE HOP AVICENNE,DEPT RADIOL F-93009 BOBIGNY FRANCE UNIV BUJUMBURA,SCH MED,DEPT MED BUJUMBURA BURUNDI SAN FRANCISCO GEN HOSP,DEPT MED SAN FRANCISCO CA 94110 UNIV CALIF SAN FRANCISCO SAN FRANCISCO CA 94143 HOP LA PITIE SALPETRIERE,DEPT RADIOL PARIS FRANCE
Titolo Testata:
American journal of respiratory and critical care medicine
fascicolo: 2, volume: 152, anno: 1995,
pagine: 794 - 799
SICI:
1073-449X(1995)152:2<794:RAITAR>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
SUB-SAHARAN AFRICA; PULMONARY TUBERCULOSIS; HIV-INFECTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
N. Mlikacabanne et al., "RADIOGRAPHIC ABNORMALITIES IN TUBERCULOSIS AND RISK OF COEXISTING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION", American journal of respiratory and critical care medicine, 152(2), 1995, pp. 794-799

Abstract

We evaluated the age profile and chest radiographic abnormalities in 158 patients from Bujumbura, Burundi, with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar/mediastinal adenopathy), to identify features that were associated with and would allow prediction of HIV seropositivity or seronegativity. Using agreed-upon criteria andprepared reporting forms, initial chest radiographs were reviewed by three readers, first independently and then at a consensus conference. Of the 158 patients, 105 (66%) were HIV seropositive and 53 patients were seronegative. Seropositive subjects (mean age, 35.8 yr) were older (p = 0.001) than seronegative subjects (mean age, 29.4 yr). Significant or borderline differences between HIV-seropositive and -seronegative patients included the frequency of small nodular lesions (p = 0.03), upper lobe cavitation (p = 0.05), and lymphadenopathy (p = 0.12), and the location of parenchymal abnormalities (p = 0.0006). Stepwise logistic regression revealed four important variables: age, small lesions, location, and lymphadenopathy; these were then used to derive an equation to calculate the probability that a given tuberculosis patient was HIV seropositive. Our mathematical model fit the observed data and the equation predicted serologic findings reasonably well. We concludethat it is possible to determine with useful probability a Burundian tuberculosis patient's HIV serologic status.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 17:22:50