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Titolo:
RADIOGRAPHIC ABNORMALITIES IN TUBERCULOSIS AND RISK OF COEXISTING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - RESULTS FROM DAR-ES-SALAAM, TANZANIA, AND SCORING SYSTEM
Autore:
MLIKACABANNE N; BRAUNER M; MUGUSI F; GRENIER P; DALEY C; MBAGA I; LAROUZE B; MURRAY JF;
Indirizzi:
IUATLD,68 BLVD ST MICHEL F-75006 PARIS FRANCE HOP CLAUDE BERNARD,INSERM,U13 PARIS FRANCE HOP AVICENNE,DEPT RADIOL F-93009 BOBIGNY FRANCE MUHIMBILI MED CTR,FAC MED,DEPT MED DAR ES SALAAM TANZANIA HOP LA PITIE SALPETRIERE,DEPT RADIOL PARIS FRANCE UNIV CALIF SAN FRANCISCO SAN FRANCISCO CA 94143 SAN FRANCISCO GEN HOSP,MED CTR,DEPT MED SAN FRANCISCO CA 94110
Titolo Testata:
American journal of respiratory and critical care medicine
fascicolo: 2, volume: 152, anno: 1995,
pagine: 786 - 793
SICI:
1073-449X(1995)152:2<786:RAITAR>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
HIV-ASSOCIATED TUBERCULOSIS; DEVELOPING-COUNTRIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
N. Mlikacabanne et al., "RADIOGRAPHIC ABNORMALITIES IN TUBERCULOSIS AND RISK OF COEXISTING HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION - RESULTS FROM DAR-ES-SALAAM, TANZANIA, AND SCORING SYSTEM", American journal of respiratory and critical care medicine, 152(2), 1995, pp. 786-793

Abstract

First, we evaluated the age profile and chest radiographic abnormalities in 146 patients from Dar-es-Salaam, Tanzania, with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar/mediastinal adenopathy), to identify features that were associated with human immunodeficiency virus (HIV) seropositivity or seronegativity; then, we combinedthese data with those from a companion investigation in Burundi to develop a simple scoring system to predict HIV serologic status. Using agreed-upon criteria and simplified reporting forms, initial chest radiographs were reviewed by three readers, first independently and then at a consensus conference. Of the 146 patients, 80 (55%) were HIV seropositive and 66 were seronegative. More seropositive than seronegative subjects were 31 to 40 yr old (p = 0.03). Because the radiographic characteristic: of the two serologic groups were similar in Tanzania and Burundi, we combined the data for stepwise logistic regression that revealed four highly significant variables: age, small lesions, location, and lymphadenopathy. From these, we obtained an equation to calculate the probability that a given tuberculosis patient was HIV seropositive and then we derived a scoring system that in its simplest form (threshold) predicted serologic status correctly in 68.1% of patients; a graded scale was even more accurate in the high (89.1%) and low (82.6%)ranges. This scoring system should be useful when serologic testing is unavailable or refused.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 08:49:44