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Titolo:
POSTERIOR SUPERIOR TEMPORAL GYRUS IN SCHIZOPHRENIA - GREY-MATTER CHANGES AND CLINICAL CORRELATES
Autore:
MENON RR; BARTA PE; AYLWARD EH; RICHARDS SS; VAUGHN DD; TIEN AY; HARRIS GJ; PEARLSON GD;
Indirizzi:
JOHNS HOPKINS UNIV HOSP,DEPT PSYCHIAT,DIV PSYCHIAT NEUROIMAGING,MEYER3-166 BALTIMORE MD 21287 JOHNS HOPKINS UNIV HOSP,DEPT PSYCHIAT,DIV PSYCHIAT NEUROIMAGING BALTIMORE MD 21287
Titolo Testata:
Schizophrenia research
fascicolo: 2, volume: 16, anno: 1995,
pagine: 127 - 135
SICI:
0920-9964(1995)16:2<127:PSTGIS>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUDITORY HALLUCINATIONS; CEREBRAL-CORTEX; GRAY-MATTER; BRAIN; LOBE; ABNORMALITIES; VOLUME; PATHOLOGY; DISORDER; IMAGES;
Keywords:
MAGNETIC RESONANCE IMAGING; SUPERIOR TEMPORAL GYRUS; THOUGHT DISORDER; (SCHIZOPHRENIA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
R.R. Menon et al., "POSTERIOR SUPERIOR TEMPORAL GYRUS IN SCHIZOPHRENIA - GREY-MATTER CHANGES AND CLINICAL CORRELATES", Schizophrenia research, 16(2), 1995, pp. 127-135

Abstract

We report an MRI morphometric study of the posterior segment of the superior temporal gyrus (STG) in twenty young male schizophrenics and their individually matched normal controls. In particular the more posterior segment of STG was examined, since it has been identified as theapproximate site of Wernicke's language area and is a marker for the planum temporale, a region believed to be abnormal in schizophrenia. Total volumes and grey and white matter volumes were measured in middleand posterior STG in each hemisphere. STG grey matter volumes and percentages were significantly reduced bilaterally in both regions in schizophrenic subjects. No significant differences between patients and controls were noted in STG white matter volumes. A significant correlation was detected between delusion scores in schizophrenics and the total volume of the left dominant posterior STG, Replicating the findingsof a recent study (Shenton et al., 1992), we found an inverse correlation between thought disorder scores and grey matter reduction in the left posterior STG in schizophrenia.

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Documento generato il 22/01/20 alle ore 13:14:49