Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ACID-BASE REACTIONS AS DRIVING-FORCE IN METABOLISM, ATP SYNTHASES ANDION-MOTIVE ATP-ASES - THE ROLE OF THE OXIDE ANION
Autore:
MADEIRA VMC;
Indirizzi:
CTR NEUROCIENCIAS P-3049 COIMBRA PORTUGAL DEPT BIOQUIM P-3049 COIMBRA PORTUGAL
Titolo Testata:
Bioelectrochemistry and bioenergetics
fascicolo: 1, volume: 38, anno: 1995,
pagine: 45 - 52
SICI:
0302-4598(1995)38:1<45:ARADIM>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
SARCOPLASMIC-RETICULUM ATPASE; CALCIUM-PUMP; RECONSTITUTED PROTEOLIPOSOMES; TRANSPORT; ENERGY; MITOCHONDRIA; ELECTRON; MEMBRANE; CA-2+; H+;
Keywords:
ATP SYNTHASES; ATP-ASES; OXIDE ANION; CHEMIOSMOSIS; CA2+ PUMP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
40
Recensione:
Indirizzi per estratti:
Citazione:
V.M.C. Madeira, "ACID-BASE REACTIONS AS DRIVING-FORCE IN METABOLISM, ATP SYNTHASES ANDION-MOTIVE ATP-ASES - THE ROLE OF THE OXIDE ANION", Bioelectrochemistry and bioenergetics, 38(1), 1995, pp. 45-52

Abstract

The basis of energy transduction often escapes the understanding of researchers since no central unified lucid theory has been provided. Inthis communication, a unified strategy in terms of basic chemical andphysico-chemical principles is proposed. Quimiotrophic and autotrophic metabolisms are centered in the role played by the oxide anion (O2-)in substrate-level phosphorylations and synthesis of organic matter; in strict association, the radical metaphosphate is used in ATP synthesis at substrate level; in turn, the metaphosphate coming from ATP is used as O2- scavenger as the central event of organosynthesis. Quimiotrophic energy transductions in aerobic and anaerobic respirations operate on the basis of a terminal oxidase as a common motif that leads tothe production of O2- stabilized in the form of H2O at expense of redox processes. Presumably, the oxidase is the operational molecular engine that pulls and drives the redox pumps. Conversely, photosynthetic systems operate in the reverse sense, with O2- derived from H2O. The electrochemical proton potential promoted by the formation of O2- (H2O)or its utilization putatively operates in ATP synthases by abstraction of O2- from orthophosphate with subsequent formation of metaphosphate that promotes ATP synthesis. Another example of O2- involvement is proposed for the Ca2+ pump ATP-ase in the basis of energetic transductions through intermediate acid-base Bohr effects associated with affinity alterations of Ca2+ binding sites through a dynamic channel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 18:15:04