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Titolo:
DETECTION OF OCCUPATIONAL LEAD NEPHROPATHY USING EARLY RENAL MARKERS
Autore:
KUMAR BD; KRISHNASWAMY K;
Indirizzi:
NATL INST NUTR,FOOD & DRUG TECHNOL RES CTR,JAMAI OSMANIA PO HYDERABAD500007 ANDHRA PRADESH INDIA NATL INST NUTR,FOOD & DRUG TECHNOL RES CTR HYDERABAD 500007 ANDHRA PRADESH INDIA
Titolo Testata:
Journal of toxicology. Clinical toxicology
fascicolo: 4, volume: 33, anno: 1995,
pagine: 331 - 335
SICI:
0731-3810(1995)33:4<331:DOOLNU>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
D-GLUCOSAMINIDASE ACTIVITY; URINARY BETA-2-MICROGLOBULIN; SMELTER WORKERS; CADMIUM; EXPOSURE; BLOOD; IMPAIRMENT; TOXICITY;
Keywords:
LEAD TOXICITY; LEAD NEPHROPATHY; OCCUPATIONAL TOXICITY; GLUCOSAMINIDASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
B.D. Kumar e K. Krishnaswamy, "DETECTION OF OCCUPATIONAL LEAD NEPHROPATHY USING EARLY RENAL MARKERS", Journal of toxicology. Clinical toxicology, 33(4), 1995, pp. 331-335

Abstract

Automotive use of leaded gasoline continues to be an important sourceof occupational exposure to lead in India and other countries. The present study assessed the renal function and markers of early renal damage of 22 mechanics at three automobile garages. Urinary N-acetyl-3-D-glucosaminidase activity and beta-2-microglobulin levels were significantly increased in auto garage mechanics with blood leads of 30-69 mu g/dL. A significant correlation was observed between blood lead levelsand urinary N-acetyl-3-D-glucosaminidase activity bur not with urine beta-2-microglobulin levels. A marginal impairment in creatinine clearance was nor statistically significant. Urinary N-acetyl-3-D-glucosaminidase activity offers a sensitive monitor of blood lead and renal tubular injury.

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Documento generato il 19/09/20 alle ore 09:31:57