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Titolo: SYNCHRONOUS FLUCTUATION OF INTERLUEKIN-6 AND PLATELET COUNT IN CYCLICTHROMBOCYTOPENIA AND THROMBOCYTOSIS
Autore: KUYAMA J; TAKE H; MATSUMOTO S; NAKAJIMA T; SUGASE T; HATA A; HANADA M; NAKAGAWA K;
- Indirizzi:
- TOYONAKA CITY HOSP,DEPT INTERNAL MED,2-1-1 OKAKAMINOCHO TOYONAKA OSAKA 560 JAPAN
- Titolo Testata:
- Internal medicine
fascicolo: 7,
volume: 34,
anno: 1995,
pagine: 636 - 639
- SICI:
- 0918-2918(1995)34:7<636:SFOIAP>2.0.ZU;2-S
- Fonte:
- ISI
- Lingua:
- ENG
- Keywords:
- MENSTRUAL CYCLE; MEGAKARYOPOIESIS; GM-CSF; TGF-BETA; STIMULATORY CYTOKINE; INHIBITORY CYTOKINE;
- Tipo documento:
- Note
- Natura:
- Periodico
- Settore Disciplinare:
- Science Citation Index Expanded
- Citazioni:
- NO
- Recensione:
- Indirizzi per estratti:
-
-
-
- Citazione:
- J. Kuyama et al., "SYNCHRONOUS FLUCTUATION OF INTERLUEKIN-6 AND PLATELET COUNT IN CYCLICTHROMBOCYTOPENIA AND THROMBOCYTOSIS", Internal medicine, 34(7), 1995, pp. 636-639
Abstract
We describe a case of cyclic thrombocytopenia and thrombocytosis, whose cytokine levels, granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin-6 (IL-6) in plasma, fluctuated in synchrony with platelet count, The levels of the two cytokines correlated significantly with the platelet count for 11 observations over an 8-month period (r=0.79, p<0.01 for GM-CSF and r=0.87, p<0.001 for IL-6), No inverse relationship between platelet-associated immunoglobulin G (PAIgG) and platelet count was observed (r=0.39, p>0.20). These findings suggestthat the fluctuation of platelet count in this case may result from an aberration of the cytokine network regulating megakaryopoiesis and platelet formation.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/21 alle ore 18:01:18