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Titolo:
METHOTREXATE THERAPY OF AMYLOIDOSIS SECON DARY TO RHEUMATOID-ARTHRITIS
Autore:
FITER J; NOLLA JM; VALVERDE J; ESCOFET DR;
Indirizzi:
C MANSO 17 6 5 E-08015 BARCELONA SPAIN HOSP PRINCEPS ESPANYA,SERV REUMATOL BARCELONA SPAIN
Titolo Testata:
Revista Clinica Espanola
fascicolo: 6, volume: 195, anno: 1995,
pagine: 390 - 392
SICI:
0014-2565(1995)195:6<390:MTOASD>2.0.ZU;2-C
Fonte:
ISI
Lingua:
SPA
Keywords:
RHEUMATOID ARTHRITIS; SECONDARY AMYLOIDOSIS; METHOTREXATE;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
J. Fiter et al., "METHOTREXATE THERAPY OF AMYLOIDOSIS SECON DARY TO RHEUMATOID-ARTHRITIS", Revista Clinica Espanola, 195(6), 1995, pp. 390-392

Abstract

Amyloidosis secondary to rheumatoid arthritis is a complication with a poor prognosis and as yet an undefined medical therapy. In the last decades the use of different cytostatics has been advocated to avoid renal function deterioration. The clinical characteristics and course in eight patients with amyloidosis secondary to rheumatoid arthritis are here reported after therapy with low dosage methotrexate. In twelve patients who followed a 12-month therapy a clinical improvement was observed, with a marked decrease in proteinuria; in one of them proteinuria disappeared. These results suggest that methotrexate at low doses might be an alternative in the early treatment of amyloidosis secondary to rheumatoid arthritis in patients with preserved renal function.

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Documento generato il 29/05/20 alle ore 17:10:20