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Titolo:
NEW ASPECTS OF THE PHYSIOLOGICAL SIGNIFICANCE OF NAD, POLY ADP-RIBOSEAND CYCLIC ADP-RIBOSE
Autore:
OKAMOTO H; TAKASAWA S; TOHGO A;
Indirizzi:
TOHOKU UNIV,SCH MED,DEPT BIOCHEM SENDAI MIYAGI 98077 JAPAN
Titolo Testata:
Biochimie
fascicolo: 5, volume: 77, anno: 1995,
pagine: 356 - 363
SICI:
0300-9084(1995)77:5<356:NAOTPS>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
PANCREATIC BETA-CELLS; EGG-SPECIFIC NADASE; DNA STRAND BREAKS; INSULIN-SECRETION; INOSITOL TRISPHOSPHATE; PROINSULIN SYNTHESIS; POLY(ADP-RIBOSE) SYNTHETASE; 2ND-MESSENGER ENZYME; ANTIGEN CD38; B-CELLS;
Keywords:
ADP-RIBOSYL CYCLASE; CYCLIC ADP-RIBOSE HYDROLASE; CD38; INSULIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
H. Okamoto et al., "NEW ASPECTS OF THE PHYSIOLOGICAL SIGNIFICANCE OF NAD, POLY ADP-RIBOSEAND CYCLIC ADP-RIBOSE", Biochimie, 77(5), 1995, pp. 356-363

Abstract

Cyclic ADP-ribose is generated from NAD(+) in glucose-stimulated beta-cells by CD38. Cyclic ADP-ribose mobilizes Ca2+ from the endoplasmic reticulum to secrete insulin. The amino acid residues of Cys-119 and Cys-201 in CD38 are essential for the synthesis and hydrolysis of cyclic ADP-ribose.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 13:16:39