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Titolo:
TRIAL OF ROUTINE GONADOTROPIN-RELEASING-HORMONE AGONIST TREATMENT BEFORE ABDOMINAL HYSTERECTOMY FOR LEIOMYOMA
Autore:
BALASCH J; MANAU D; MIMO J; DURAN M; PUERTO B; VANRELL JA;
Indirizzi:
UNIV BARCELONA,HOSP CLIN & PROV,FAC MED,DEPT OBSTET & GYNECOL,C CASANOVA 143 E-08036 BARCELONA SPAIN
Titolo Testata:
Acta obstetricia et gynecologica Scandinavica
fascicolo: 7, volume: 74, anno: 1995,
pagine: 562 - 565
SICI:
0001-6349(1995)74:7<562:TORGAT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
UTERINE LEIOMYOMAS; RANDOMIZED TRIAL; UNITED-STATES; FIBROIDS; WOMEN; ANALOGS; THERAPY;
Keywords:
GONADOTROPIN RELEASING HORMONE AGONISTS; HYSTERECTOMY; LEIOMYOMA; OPERATIVE COMPLICATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
J. Balasch et al., "TRIAL OF ROUTINE GONADOTROPIN-RELEASING-HORMONE AGONIST TREATMENT BEFORE ABDOMINAL HYSTERECTOMY FOR LEIOMYOMA", Acta obstetricia et gynecologica Scandinavica, 74(7), 1995, pp. 562-565

Abstract

Objective. To investigate the usefulness of a routine short term treatment with gonadotropin releasing hormone agonist (D-Trp-6-LHRH depot)before abdominal hysterectomy for leiomyoma. Study Design. Prospective, comparative, randomized study. Setting. A teaching hospital of Barcelona University. Patients. Fifty premenopausal women requiring hysterectomy as treatment for symptomatic leiomyomas. Twenty-three patients were randomized to receive gonadotropin releasing hormone agonist treatment before hysterectomy (cases), and 27 patients were randomized to immediate hysterectomy (controls). Main outcome measures. Type of abdominal incision, operating time, operative hemoglobin and hematocrit decrease, postoperative morbidity, and days in hospital. Results. In theagonist treated group mean uterine volume decreased and mean hemoglobin and hematocrit significantly rose after 8 weeks of treatment. Operative time was similar in both groups of patients but the number of women having Pfannenstiel incision was significantly higher in the cases. Mean operative hemoglobin and hematocrit decrease and postoperative morbidity were lower in the cases. There was a trend for shorter postoperative hospital stays in the agonist treated group. Conclusions. Our results favor the routine use of a short term gonadotropin releasing hormone agonist treatment before abdominal hysterectomy for leiomyoma in order to decrease operative blood loss and postoperative morbidity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:46:03