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Titolo:
DIFFUSE VESICULAR DISTRIBUTION OF RAB3D IN THE POLARIZED NEUROENDOCRINE CELL-LINE ATT-20
Autore:
MARTELLI AM; BAREGGI R; BALDINI G; SCHERER PE; LODISH HF; BALDINI G;
Indirizzi:
COLUMBIA UNIV COLL PHYS & SURG,DEPT ANAT & CELL BIOL,630 W 168TH ST NEW YORK NY 10032 COLUMBIA UNIV COLL PHYS & SURG,DEPT ANAT & CELL BIOL NEW YORK NY 10032 DIPARTIMENTO MORFOL UMANA NORMALE I-34138 TRIESTE ITALY WHITEHEAD INST BIOMED RES CAMBRIDGE MA 02142 MIT,DEPT BIOL CAMBRIDGE MA 02139
Titolo Testata:
FEBS letters
fascicolo: 2, volume: 368, anno: 1995,
pagine: 271 - 275
SICI:
0014-5793(1995)368:2<271:DVDORI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYNAPTIC VESICLES; ADIPOCYTES; CLONING; INSULIN;
Keywords:
LOW MOLECULAR WEIGHT GTP-BINDING PROTEIN; REGULATED SECRETION; ATT-20 ENDOCRINE CELL LINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Martelli et al., "DIFFUSE VESICULAR DISTRIBUTION OF RAB3D IN THE POLARIZED NEUROENDOCRINE CELL-LINE ATT-20", FEBS letters, 368(2), 1995, pp. 271-275

Abstract

The neuroendocrine cell line AtT-20 has two types of storage vesicles: dense core granules and synaptic vesicles, both sequestered at the tip of the processes. Here we show that Rab3D protein, which is abundant in fat cells, is also expressed in AtT-20 cells. Differently from Rab3A, which is localized in secretory vesicles accumulated at the tips,Rab3D has a diffuse vesicular distribution in the cytoplasm of the cell body, the processes and the tips. In AtT-20 cells, Rab3D may definea regulated secretory pathway which functions independently from cellpolarity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 12:53:08