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Titolo:
RADIOTHERAPY OF ECTOPIC ACTH SYNDROME DUE TO THORACIC CARCINOIDS
Autore:
HE JL; ZHOU JC; LU ZL;
Indirizzi:
BEIJING UNION MED COLL HOSP,DEPT RADIAT ONCOL BEIJING 100730 PEOPLES R CHINA BEIJING UNION MED COLL HOSP,DEPT ENDOCRINOL BEIJING 100730 PEOPLES R CHINA
Titolo Testata:
Chinese medical journal
fascicolo: 5, volume: 108, anno: 1995,
pagine: 338 - 341
SICI:
0366-6999(1995)108:5<338:ROEASD>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUSHINGS-SYNDROME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
J.L. He et al., "RADIOTHERAPY OF ECTOPIC ACTH SYNDROME DUE TO THORACIC CARCINOIDS", Chinese medical journal, 108(5), 1995, pp. 338-341

Abstract

From 1984 to 1990, six patients with histologically and endocrinologically proven ectopic ACTH syndrome were treated in our department. Thelesion in five patients was clinically evident, but in the other was occult. Ah lesions were located within the chest. Four were thymic carcinoid and the other two were bronchial carcinoids. Most of the patients had typical clinical manifestations of Gushing's syndrome. Laboratory tests including histopathological examination confirmed the diagnosis of ectopic ACTH syndrome. The treatment consisted of surgical removal of the mass supplemented by radiotherapy. The results showed that after treatment all patients had satisfactory remission. Two bronchial carcinoid patients have been living for 40 and 88 months respectively without recurrence. Among 4 thymic carcinoid patients, only one has been living with no tumor for 34 months. One patient had recurrence and the other 2 died 32 and 50 months after the treatment respectively. However, the symptoms of two thymic carcinoid patients had not been relieved at all unitl radiotherapy was given. This paper discusses the method, dose and indications of radiotherapy. It should be pointed out that the prognosis of bronchial carcinoids is good while that of thymic carcinoids is relatively poor.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 16:09:31