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Titolo:
VASCULAR COMPLICATIONS IN PATIENTS WITH ALDOSTERONE-PRODUCING ADENOMAIN JAPAN - COMPARATIVE-STUDY WITH ESSENTIAL-HYPERTENSION
Autore:
TAKEDA R; MATSUBARA T; MIYAMORI I; HATAKEYAMA H;
Indirizzi:
KANAZAWA UNIV,SCH MED,DEPT INTERNAL MED 2,TAKARA MACHI 13-1 KANAZAWA ISHIKAWA 920 JAPAN
Titolo Testata:
Journal of endocrinological investigation
fascicolo: 5, volume: 18, anno: 1995,
pagine: 370 - 373
SICI:
0391-4097(1995)18:5<370:VCIPWA>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
RENIN;
Keywords:
ALDOSTERONE-PRODUCING ADENOMA; CEREBRAL HEMORRHAGE; CEREBRAL INFARCTION; MYOCARDIAL INFARCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
R. Takeda et al., "VASCULAR COMPLICATIONS IN PATIENTS WITH ALDOSTERONE-PRODUCING ADENOMAIN JAPAN - COMPARATIVE-STUDY WITH ESSENTIAL-HYPERTENSION", Journal of endocrinological investigation, 18(5), 1995, pp. 370-373

Abstract

The incidence of vascular complications in 224 patients with aldosterone-producing adenoma (APA) which was proven on adrenal surgery, was compared to that in 224 sex- and age-matched patients with essential hypertension (EHT). The incidence of cerebral hemorrhage was significantly higher (p<0.05) in the patients with APA when compared to the EHT group. On the other hand, the incidence of myocardial infarction and/orcongestive heart failure in the APA group was lower, although this difference did not reach statistical significance. Diastolic blood pressure in the APA group was significantly higher (p<0.001) in the EHT group. However, a significant difference in diastolic blood pressure was not detected between the APA groups with and without vascular complications, whereas in the EHT group diastolic blood pressure was significantly higher (p<0.001) in cases with vascular complications as comparedto those without complications. As a possible factor contributing to the higher incidence of cerebral hemorrhage in the APA group, proteinuria was suggested. It was recommended that patients with primary aldosteronism should undergo operation when localization of the APA is established.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 17:02:22