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Titolo:
IDENTIFICATION OF A NEW MEMBER OF THE HUMAN EIF-5A GENE FAMILY
Autore:
KOETTNITZ K; WOHL T; KAPPEL B; LOTTSPEICH F; HAUBER J; BEVEC D;
Indirizzi:
SANDOZ GMBH,FORSCHUNGSINST,BRUNNER STR 59 A-1235 VIENNA AUSTRIA SANDOZ GMBH,FORSCHUNGSINST A-1235 VIENNA AUSTRIA MAX PLANCK INST BIOCHEM D-82152 MARTINSRIED GERMANY
Titolo Testata:
Gene
fascicolo: 2, volume: 159, anno: 1995,
pagine: 283 - 284
SICI:
0378-1119(1995)159:2<283:IOANMO>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
EUKARYOTIC INITIATION FACTOR-5A; HYPUSINE-CONTAINING PROTEIN;
Keywords:
COSMID CLONE; TRANSLATION INITIATION FACTOR; HIV-1 REV COFACTOR; 5'-RACE PCR; EXON-INTRON ORGANIZATION; YEAST COMPLEMENTATION; SACCHAROMYCES;
Tipo documento:
Note
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
K. Koettnitz et al., "IDENTIFICATION OF A NEW MEMBER OF THE HUMAN EIF-5A GENE FAMILY", Gene, 159(2), 1995, pp. 283-284

Abstract

Using an oligodeoxynucleotide generated by rapid PCR amplification of5'-cDNA ends (5'-RACE) as a detection probe, we have isolated a new genomic clone encoding the human eukaryotic initiation factor 5A (eIF-5A), Sequence analysis revealed that the eIF-5A coding region is identical to the corresponding cDNA but interrupted by three introns, In a plasmid shuffle experiment we show functional replacement of the essential homologous gene in Saccharomyces cerevisiae by this human eIF-5A.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 00:23:53