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Titolo:
GENDER-RELATED DIFFERENCES IN THE DISTRIBUTION OF THORACIC VERSUS ABDOMINAL MALIGNANT MESOTHELIOMA
Autore:
DELFINO RJ; ANTONCULVER H; SALTZSTEIN SL;
Indirizzi:
UNIV CALIF IRVINE,CALIF COLL MED,DEPT MED,PROGRAM EPIDEMIOL IRVINE CA92717
Titolo Testata:
Cancer detection and prevention
fascicolo: 4, volume: 19, anno: 1995,
pagine: 301 - 307
SICI:
0361-090X(1995)19:4<301:GDITDO>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Keywords:
ASBESTOS; HEREDITY; EPIDEMIOLOGY; REGISTRY; INCIDENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
R.J. Delfino et al., "GENDER-RELATED DIFFERENCES IN THE DISTRIBUTION OF THORACIC VERSUS ABDOMINAL MALIGNANT MESOTHELIOMA", Cancer detection and prevention, 19(4), 1995, pp. 301-307

Abstract

The relationship between malignant mesothelioma (MM) and asbestos is well. established, but the determinants of host factor susceptibility to MM are not. This study probes susceptibility issues by examining gender-related differences in the distribution of 417 thoracic and 42 abdominal cases of MM from 1988-1989 California Cancer Registry databases. The age-adjusted incidence rate ratio (IRR) for male/female thoracic MM was 6.9 (95% confidence interval [CI]: 5.0-9.6) consistent with greater occupational exposure among men. However, the IRR for male/female abdominal MM was 1.5 (95% CI: 0.6-3.6). Also, average age of onset for thoracic MM was greater than for abdominal MM. Thus, some abdominal MMs may be due to nonoccupational asbestos exposure, occurring over a lifetime, interacting with host factor susceptibility. This study gives impetus to research regarding the importance of host factors and nonoccupational asbestos exposure in the etiology of malignant mesothelioma.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 11:42:16