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Titolo:
TOPOGRAPHIC CHANGES IN A HETEROCHROMATIC CHROMOSOME BLOCK IN HUMANS (15P) DURING FORMATION OF THE NUCLEOLUS
Autore:
KAPLAN FS; OCONNOR JP;
Indirizzi:
HOSP UNIV PENN,DEPT ORTHOPAED,3400 SPRUCE ST,SILVERSTEIN 2 PHILADELPHIA PA 19104 UNIV PENN,SCH MED,DEPT BIOCHEM & BIOPHYS PHILADELPHIA PA 19104 HOWARD HUGHES MED INST PHILADELPHIA PA 19104
Titolo Testata:
Chromosome research
fascicolo: 5, volume: 3, anno: 1995,
pagine: 309 - 314
SICI:
0967-3849(1995)3:5<309:TCIAHC>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN ACROCENTRIC CHROMOSOMES; SCANNING ELECTRON-MICROSCOPY; REPETITIVE DNA-SEQUENCES; ALPHA-SATELLITE DNA; RIBOSOMAL-RNA GENES; INSITU HYBRIDIZATION; CONFOCAL MICROSCOPY; PREFORMED RNA; ORGANIZATION; METAPHASE;
Keywords:
CHROMOSOMES; DECONDENSED HETEROCHROMATIN; MITOSIS; NUCLEOLUS; SATELLITE DNA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
51
Recensione:
Indirizzi per estratti:
Citazione:
F.S. Kaplan e J.P. Oconnor, "TOPOGRAPHIC CHANGES IN A HETEROCHROMATIC CHROMOSOME BLOCK IN HUMANS (15P) DURING FORMATION OF THE NUCLEOLUS", Chromosome research, 3(5), 1995, pp. 309-314

Abstract

Fluorescence in situ hybridization and multispectral confocal laser scanning microscopy revealed a highly dynamic nucleolar-associated chromosome 15 satellite III heterochromatin cluster in humans. This nucleolar-associated DNA was highly decondensed at the metaphase plate compared with its topography at interphase and appeared to act as a centre for the postmitotic reorganization of the nucleolus. Our data showed unexpected trans-mitotic changes in the topography of this nucleolar-associated satellite III DNA that suggest that this locus-specific heterochromatin superstructure may be involved in nucleolar organization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 11:01:06