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Titolo:
VECTORCARDIOGRAPHY IN EXPERIMENTAL MYOCARDIAL-INFARCTION - SERIAL CHANGES AND CORRELATION BETWEEN QRS LOOP CHANGE AND THE INFARCTION SIZE
Autore:
TSENG CD; TSENG YZ; CARSON W; PHIL D; LO HM; HSU KL; CHIANG FT; WU TL;
Indirizzi:
NATL TAIWAN UNIV HOSP,DEPT INTERNAL MED,7 CHUN SUN S RD TAIPEI 100 TAIWAN
Titolo Testata:
Japanese Heart Journal
fascicolo: 3, volume: 36, anno: 1995,
pagine: 349 - 365
SICI:
0021-4868(1995)36:3<349:VIEM-S>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Keywords:
VECTORCARDIOGRAPHY; QRS LOOP; ACUTE MYOCARDIAL INFARCTION; INFARCT SIZE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
C.D. Tseng et al., "VECTORCARDIOGRAPHY IN EXPERIMENTAL MYOCARDIAL-INFARCTION - SERIAL CHANGES AND CORRELATION BETWEEN QRS LOOP CHANGE AND THE INFARCTION SIZE", Japanese Heart Journal, 36(3), 1995, pp. 349-365

Abstract

The objectives of this study were to examine the serial vectorcardiographic changes following acute myocardial infarct and to assess the relationship between QRS loop changes and infarct size. Fifty adult maleLong-Evans rats of 250-350 gm body weight were used to study experimental acute myocardial infarction induced by coronary artery ligation. Vectorcardiograms (VCG) of the Frank lead system were recorded before,and 1 day and 7 days after operation. Animals were sacrificed on the 7th day for histological quantitation of infarct area ratios. We foundthat (1) before operation, rats have ST elevation, probably due to early repolarization. (2) After coronary artery ligation, ECG showed characteristic dome-shaped ST elevation at 1 hr after ligation which returned to normal during the first day. Abnormal Q waves appeared thereafter. (3) After ligation, maximum QRS-vector, ST vector and maximum T vector were reduced in magnitude the first day and recovered by the 7thday. The vectors tended to shift their direction to the right and to the posterior. QRS-T angle, however, widened as time went on. About half of the rats revealed changes in the inscription direction of the QRS loop and abnormal QRS morphology also appeared in about half of the ligated rats. (4) Those in whom abnormal QRS loop morphology and/or biting appeared had significantly larger infarct area ratios (p<0.01). (5) Change in QRS loop inscription direction seemed not to be related to the infarct size. (6) In the LS plane, the difference in max QRS vector magnitude between the 1st and 7th days significantly correlated with the infarct area ratio (r=0.533, P<0.05). In the H plane, the change in the max QRS vector magnitude at the 7th day correlated with the infarct area ratio (r=-0.531, P<0.05). In the F plane, changes in the direction of the max QRS vector were significantly correlated to the infarct area ratio both on the first (r=0.431, P<0.05) and 7th days (r=0.531, p<0.05). It is concluded that the VCG, like the EGG, had evolutional changes in AMI and that the QRS loop seen on vectorcardiography has only a slight correlation with the histological myocardial infarct size.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 20:44:39