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Titolo:
INTERACTIONS BETWEEN CHRONIC VIRAL-HEPATI TIS-C AND PREGNANCY
Autore:
GRANGE JD; ABERGEL A; AMIOT X; CHASLINFERBUS D; AYGALENQ P; FOUQUERAY B; VALLA D; BOMMELAER G; BODIN F;
Indirizzi:
HOP TENON,SERV HEPATOGASTROENTEROL F-75970 PARIS 20 FRANCE HOP TENON,SERV HEPATOGASTROENTEROL F-75020 PARIS FRANCE HOP TENON,EXPLORAT FONCT LAB F-75020 PARIS FRANCE HOP HOTEL DIEU,SERV HEPATOGASTROENTEROL F-63000 CLERMONT FERRAND FRANCE HOP LA PITIE SALPETRIERE,SERV HEPATOGASTROENTEROL F-75013 PARIS FRANCE
Titolo Testata:
Gastroenterologie clinique et biologique
fascicolo: 5, volume: 19, anno: 1995,
pagine: 520 - 524
SICI:
0399-8320(1995)19:5<520:IBCVTA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
FRE
Soggetto:
POLYMERASE CHAIN-REACTION; TO-INFANT TRANSMISSION; LIVER-DISEASE; VIRUS-RNA; NON-A; NON-B; LEUKEMIA; THERAPY; PATIENT; WOMEN;
Keywords:
CHRONIC HEPATITIS; ANTI-HCV ANTIBODIES; PREGNANCY; VIRUS C;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
29
Recensione:
Indirizzi per estratti:
Citazione:
J.D. Grange et al., "INTERACTIONS BETWEEN CHRONIC VIRAL-HEPATI TIS-C AND PREGNANCY", Gastroenterologie clinique et biologique, 19(5), 1995, pp. 520-524

Abstract

Objectives and methods. - In France, the positive rate for anti-HCV antibodies in the sera of pregnant women is usually found to be between0.7 and 3.9 %. The aim of our prospective study was to determine the interactions between pregnancy and chronic viral hepatitis C in 12 pregnant women. Results. - In our study, chronic viral hepatitis C did not influence maternal or neonatal outcome. The mean gestational age was38.4 +/- 3 weeks. During follow-up, mean serum ALT levels were significantly lower (36 +/- 17 mU/mL) during the last three months of pregnancy compared to before pregnancy (237 +/- 144 mU/mL, P < 0.002) and after pregnancy (141 +/- 62 mU/mL, P < 0.0005). During the third trimester, serum ALT levels were normal in 90 % of the women. However, the persistence of viremia during pregnancy and a rebound in serum ALT during the post-partum period have been noticed. Conclusion. - The normalization of serum ALT levels during pregnancy, the persistence of viremia, and a rebound in serum ALT during post-partum could be related to pregnancy-induced changes in the immune system.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 19:30:14